Hep C Discussion Forum

Tig · Tig

This is a worthwhile article. It’s just a summary, but maps things pretty well. Check it out, I bet it brings back some memories, for most anyway... CDC 2020

Tig · Tig

Hello, I've been receiving these articles from HepVu and wanted to pass along their website. It's a very informative website and organization. I recommend you take a moment and look around the information provided. The infection rate by state is an interesting map. We've got a long way to go before w...

Tig · Tig

I received notice of a Hepatitis A outbreak in the USA, resulting from blackberries. Please read! Hep A Warning

emilyjones · emilyjones

Uses. Daclatasvir is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Daclatasvir should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medica...

Canuck · Canuck

Another "new?" NS5A - "Ruzasvir" - Info from drug study discussed at recent Nov 2106 Boston Meeting.We have heard a lot about Zepatier (elbasvir/ grazoprevir) a NS5A and a NS3/4A respectively (given with or without riba, and sometimes with sof), but I (personally) did not know about this (new to m...

Canuck · Canuck

Published in GastroenterologyJournal Scan / Research · May 20, 2019Resistance Analysis of Genotype 3 HCV Indicates Subtypes Inherently Resistant to Nonstructural Protein 5A InhibitorsHepatology (Baltimore, Md.)TAKE-HOME MESSAGEThis is an interesting study wherein the authors eva...

Canuck · Canuck

California health officials battle state's largest hepatitis A outbreak in 2 decadesHelio - July 21, 2017The California Department of Public Health is working with local health officials in San Diego and Santa Cruz counties to contain the state's largest hepatitis A outbreak in 2 decades.As of J...

Canuck · Canuck

We have discussed the use of AFP's (many times, all over this site) but of late in particular about how an AFP may be used to possibly herald other kinds of cancers developing, aside from liver cancer, and it lead us to discuss not only the good ole familiar AFP, but the less US-used one, the AFP-L3 (this o...

Tig · Tig

This is very good news for those of us keeping an eye on our blood glucose levels! SVR brings improvements in areas we might not realize. It takes time to see some of these changes, but knowing it happens, is good news for all! A1C Reductions

jagad001 · jagad001

I ran my own company for several years, and I was always on the go. Sometime around 2010 or later, I began to feel tired all the time. I went to doctors, and they kept ordering lab tests, such as checking for diabetes. They couldnt find anything wrong with me for a year or two, so eventually I stopped going t...

Canuck · Canuck

I think it was "dharmabum" who first raised the early alarm about some sort of "recall" going on with a med (that I think she was on), Losartan (perhaps it was some other Losartan formula name she mentioned), but I do believe this Losartan drug was the one she referred to and was concerned about (I looked...

Cheddy · Cheddy

HEY NEW MEMBERS, IF HE CAN DO IT, SO CAN YOU! WE'VE MADE SO MUCH PROGRESS! NEWS RELEASEJanuary 16, 2019For immediate releaseRegions 1st hepatitis C heart-transplant recipient is curedAnacortes, Wash., man opted into UW Medicine protocol to receive infected donor heart and then had virus eradi...

Canuck · Canuck

Not that in North America we have seen Dacla (a NS5A) and Asunaprevir (a NS3/4A) being used as a double, but in Japan they have made use of this double. Multiple Japanese studies have fairly recently been coming out about the prevalent use of this combo and various notes they are making about it. This st...

Tig · Tig

I found this recent article on our favorite topic, HCV. I found it to be a good description of it and the many issues that accompany it. It’s easy to understand and could be a good tool for us to present when asked about the disease. See what you think. I give it a 9 out of 10... Everything You Need to Know: HCV...

Canuck · Canuck

From "Contagion Live - Infectious Diseases Today": ARTICLE Hepatitis C Treatment Time Could Be Cut in Half in Some Patients: A Proof of Concept Study NOV 14, 2018 | EINAV KEET A personalized medicine technique may shorten the duration and reduce the cost of treatment for hepatitis C virus infecti...

dharmabum · dharmabum

http://time.com/4996657/heart-transplant-hepatitis-c/

Tig · Tig

The AASLD and IDSA HCV Guidance Panel has released updated guidelines for the treatment of hepatitis C virus infection, according to newly published data in Hepatology. You will note that they continue to recommend the use of 12 weeks of Sovaldi/Peg Interferon/Ribavirin in GT 3's that are able to...

Canuck · Canuck

So, this article/take-home message, about the study (and the study itself) I found interesting - and, oh of course, they just had to study the costs savings! The part that was interesting to me was that group of liver transplant people who were studied and followed between 1998 and 2015, who WERE tole...

Canuck · Canuck

A relatively "new?" NS5A - (formerly called PP1-668), now named Ravidasvir. Well, it's news to me anyway. Out of Egypt (where there are many GT4's to trial it on), but reading other articles about it tonight, it IS being touted as pan, coupled with sof, with some impressive results, and more interest...

Canuck · Canuck

https://hepatitiscnewdrugs.blogspot.com/2011/03/celebrities-with-hepatiti...

Tig · Tig

This slide set was published last year, but offers some interesting info for new and old members alike. I couldn’t locate it being brought here before and CCO is more often a physician only periodical most don’t have access to. It’s amazing to see the shear numbers affected by this disease globally an...

sleestak · sleestak

Thanks to the cultural mediator support, we explained to the patient the correct posology of each drug to take during the day consisting of 12 week SOF (400 mg daily) plus DCV (60 mg daily) regimen. He returned 13 days after for a programmed visit and we were surprised to learn that he had taken 3 pills o...

Canuck · Canuck

From: MedscapeNews > Reuters Health InformationExtrahepatic Manifestations of Chronic Hep C Improve With Sustained Virological ResponseBy Will Boggs MDMay 21, 2018 NEW YORK (Reuters Health) - Extrahepatic manifestations of chronic hepatitis C virus (HCV) infection improve or res...

Tig · Tig

EASL Paris 2018 Updates c/o Clinical Care Options - Hepatitis Review Capsules Summaries, download slides, and listen to audio commentary from expert-led Webinars covering critical studies on viral hepatitis and NAFLD/NASH from Paris. credit: Clinical Care Options

Tig · Tig

Gilead, Inc., The World Health Organization has established a goal of eliminating viral hepatitis (hepatitis B and hepatitis C) by the year 2030.In support of this target, Gilead’s Medical Affairs team has created the CHIME Program (Conquering Hepatitis via Micro-Elimination), offering r...

Tig · Tig

YOU'RE INVITED!ALF CT Liver Transplant ReBirthday PartyApril is National Donate Life Month. The American Liver Foundation recognizes the incredible gift of life through transplantation.The Liver Tranplant ReBirthday Party is a gathering to hear liver transplantation updates from Con...

Canuck · Canuck

There was a fair bit of "talk" in the Journals, about safety profiles, and "Shingrex" getting approved for use over the "live" Zostavax in 2018. Between 2015 and as late as 2017 studies were still being completed about the effectiveness of Hep B and Zostavax immunizations in folk in association wit...

Canuck · Canuck

Funny (not) how "real world" data takes so long to "come out"! Here is a recent publication (2018), all about "Viekirax" (ombitasvir/paritaprevir/ritonavir) and "Exviera" (dasabuvir) - also known as "OPrD" (similar to later and further formulations named Viekira Pak and then Viekira XR).B...

skewedButNotBroken · skewedButNotBroken

https://www.hepmag.com/article/HCV-Brain-Endothelium-21818-1287637502

Canuck · Canuck

Published in Gastroenterology - News · January 18, 2018Psoriasis Remission Described After Hepatitis C Virus TreatmentCase report: After initiation of ledipasvir-sofosbuvir, HCV RNA decreased, and skin lesions improvedHealthDay WEDNESDAY, Jan. 17, 2018 (HealthDay News) -- A case of...

Topic		Started By	Replies	Views	Last Post
	CDC Recommendations (Preview) This is a worthwhile article. It’s just a summary, but maps things pretty well. Check it out, I bet it brings back some memories, for most anyway... CDC 2020	Tig	0	1540	Jun 7, 2020 by Tig
	HepVu Updates (Preview) Hello, I've been receiving these articles from HepVu and wanted to pass along their website. It's a very informative website and organization. I recommend you take a moment and look around the information provided. The infection rate by state is an interesting map. We've got a long way to go before w...	Tig	0	1902	Jan 15, 2020 by Tig
	Hep A Food Warning Dec.2019 (Preview) I received notice of a Hepatitis A outbreak in the USA, resulting from blackberries. Please read! Hep A Warning	Tig	0	1444	Dec 11, 2019 by Tig
	What is Daclatasvir used for? (Preview) Uses. Daclatasvir is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Daclatasvir should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medica...	emilyjones	0	1088	Oct 31, 2019 by emilyjones
	New Contenders?? NS5A Ruzasvir and NS5B MK-3682 (Preview) Another "new?" NS5A - "Ruzasvir" - Info from drug study discussed at recent Nov 2106 Boston Meeting.We have heard a lot about Zepatier (elbasvir/ grazoprevir) a NS5A and a NS3/4A respectively (given with or without riba, and sometimes with sof), but I (personally) did not know about this (new to m...	Canuck	8	4243	Jun 12, 2019 by Canuck
	GT3's - (and more so, maybe "certain" GT3 sub-types) - perhaps why we have most often been considered "hard to treat" (Preview) Published in GastroenterologyJournal Scan / Research · May 20, 2019Resistance Analysis of Genotype 3 HCV Indicates Subtypes Inherently Resistant to Nonstructural Protein 5A InhibitorsHepatology (Baltimore, Md.)TAKE-HOME MESSAGEThis is an interesting study wherein the authors eva...	Canuck	2	2050	Jun 4, 2019 by Tig
	Up-surge of Hep A in California (Preview) California health officials battle state's largest hepatitis A outbreak in 2 decadesHelio - July 21, 2017The California Department of Public Health is working with local health officials in San Diego and Santa Cruz counties to contain the state's largest hepatitis A outbreak in 2 decades.As of J...	Canuck	36	6161	May 26, 2019 by Cheddy
	HCC Detection - Using AFP, AFP-L3 and DCP (Preview) We have discussed the use of AFP's (many times, all over this site) but of late in particular about how an AFP may be used to possibly herald other kinds of cancers developing, aside from liver cancer, and it lead us to discuss not only the good ole familiar AFP, but the less US-used one, the AFP-L3 (this o...	Canuck	1	1089	May 24, 2019 by 5-1-18
	Significant A1C reduction after SVR (Preview) This is very good news for those of us keeping an eye on our blood glucose levels! SVR brings improvements in areas we might not realize. It takes time to see some of these changes, but knowing it happens, is good news for all! A1C Reductions	Tig	1	1136	May 9, 2019 by Cheddy
	Cure of hepatitis C (Preview) I ran my own company for several years, and I was always on the go. Sometime around 2010 or later, I began to feel tired all the time. I went to doctors, and they kept ordering lab tests, such as checking for diabetes. They couldnt find anything wrong with me for a year or two, so eventually I stopped going t...	jagad001	6	1923	Mar 26, 2019 by Tig
	BP Med - Losartan (and recalls, and fibrosis) (Preview) I think it was "dharmabum" who first raised the early alarm about some sort of "recall" going on with a med (that I think she was on), Losartan (perhaps it was some other Losartan formula name she mentioned), but I do believe this Losartan drug was the one she referred to and was concerned about (I looked...	Canuck	0	1798	Mar 24, 2019 by Canuck
	Region's 1st HCV heart-transplant is Cured WOW (Preview) HEY NEW MEMBERS, IF HE CAN DO IT, SO CAN YOU! WE'VE MADE SO MUCH PROGRESS! NEWS RELEASEJanuary 16, 2019For immediate releaseRegions 1st hepatitis C heart-transplant recipient is curedAnacortes, Wash., man opted into UW Medicine protocol to receive infected donor heart and then had virus eradi...	Cheddy	2	1746	Jan 17, 2019 by Tig
	Dacla and Asunaprevir (Preview) Not that in North America we have seen Dacla (a NS5A) and Asunaprevir (a NS3/4A) being used as a double, but in Japan they have made use of this double. Multiple Japanese studies have fairly recently been coming out about the prevalent use of this combo and various notes they are making about it. This st...	Canuck	0	1222	Dec 22, 2018 by Canuck
	HCV: Explained 2018 (Preview) I found this recent article on our favorite topic, HCV. I found it to be a good description of it and the many issues that accompany it. It’s easy to understand and could be a good tool for us to present when asked about the disease. See what you think. I give it a 9 out of 10... Everything You Need to Know: HCV...	Tig	0	2077	Dec 11, 2018 by Tig
	Shortening HCV Treatment Courses (Preview) From "Contagion Live - Infectious Diseases Today": ARTICLE Hepatitis C Treatment Time Could Be Cut in Half in Some Patients: A Proof of Concept Study NOV 14, 2018 \| EINAV KEET A personalized medicine technique may shorten the duration and reduce the cost of treatment for hepatitis C virus infecti...	Canuck	0	1789	Nov 24, 2018 by Canuck
	Organ Donors (Preview) http://time.com/4996657/heart-transplant-hepatitis-c/	dharmabum	5	2506	Nov 14, 2018 by Canuck
	AASLD/IDSA release updated HCV treatment guidelines (Preview) The AASLD and IDSA HCV Guidance Panel has released updated guidelines for the treatment of hepatitis C virus infection, according to newly published data in Hepatology. You will note that they continue to recommend the use of 12 weeks of Sovaldi/Peg Interferon/Ribavirin in GT 3's that are able to...	Tig	1	2469	Nov 5, 2018 by Tig
	Liver Transplant Article (Preview) So, this article/take-home message, about the study (and the study itself) I found interesting - and, oh of course, they just had to study the costs savings! The part that was interesting to me was that group of liver transplant people who were studied and followed between 1998 and 2015, who WERE tole...	Canuck	0	1187	Oct 27, 2018 by Canuck
	A "new?" NS5A - "PP1-668" (Ravidasvir) (Preview) A relatively "new?" NS5A - (formerly called PP1-668), now named Ravidasvir. Well, it's news to me anyway. Out of Egypt (where there are many GT4's to trial it on), but reading other articles about it tonight, it IS being touted as pan, coupled with sof, with some impressive results, and more interest...	Canuck	11	8547	Oct 23, 2018 by Canuck
	2011 HCV Blog News (Preview) https://hepatitiscnewdrugs.blogspot.com/2011/03/celebrities-with-hepatiti...	Canuck	0	1246	Sep 9, 2018 by Canuck
	Clinical Care Options: Tools for HCV Care (Preview) This slide set was published last year, but offers some interesting info for new and old members alike. I couldn’t locate it being brought here before and CCO is more often a physician only periodical most don’t have access to. It’s amazing to see the shear numbers affected by this disease globally an...	Tig	2	1611	Aug 26, 2018 by Tig
	SVR 24 Two Weeks After a Tripled Dose of Daclatasvir in an HCV Genotype 3 Patient (Preview) Thanks to the cultural mediator support, we explained to the patient the correct posology of each drug to take during the day consisting of 12 week SOF (400 mg daily) plus DCV (60 mg daily) regimen. He returned 13 days after for a programmed visit and we were surprised to learn that he had taken 3 pills o...	sleestak	3	2126	Jun 18, 2018 by Canuck
	Extrahepatic Manifestation Improvements After SVR (Preview) From: MedscapeNews > Reuters Health InformationExtrahepatic Manifestations of Chronic Hep C Improve With Sustained Virological ResponseBy Will Boggs MDMay 21, 2018 NEW YORK (Reuters Health) - Extrahepatic manifestations of chronic hepatitis C virus (HCV) infection improve or res...	Canuck	1	2028	May 23, 2018 by Tig
	EASL 2018 Updates: Paris (Preview) EASL Paris 2018 Updates c/o Clinical Care Options - Hepatitis Review Capsules Summaries, download slides, and listen to audio commentary from expert-led Webinars covering critical studies on viral hepatitis and NAFLD/NASH from Paris. credit: Clinical Care Options	Tig	3	2164	May 5, 2018 by Canuck
	Conquering Hep B/C via Micro-Elimination (Preview) Gilead, Inc., The World Health Organization has established a goal of eliminating viral hepatitis (hepatitis B and hepatitis C) by the year 2030.In support of this target, Gilead’s Medical Affairs team has created the CHIME Program (Conquering Hepatitis via Micro-Elimination), offering r...	Tig	0	1834	Apr 23, 2018 by Tig
	ALF CT Liver Transplant ReBirthday Party (Preview) *YOU'RE INVITED!ALF CT Liver Transplant ReBirthday PartyApril is* National Donate Life Month. The American Liver Foundation recognizes the incredible gift of life through transplantation.The Liver Tranplant ReBirthday Party is a gathering to hear liver transplantation updates from Con...	Tig	2	2303	Mar 29, 2018 by Canuck
	Herpes Zoster Vaccination - "Shingrex" versus "Zostavax" (Preview) There was a fair bit of "talk" in the Journals, about safety profiles, and "Shingrex" getting approved for use over the "live" Zostavax in 2018. Between 2015 and as late as 2017 studies were still being completed about the effectiveness of Hep B and Zostavax immunizations in folk in association wit...	Canuck	5	3024	Mar 11, 2018 by Canuck
	Viekirax and Exviera (OPrD) - Real World Data (Preview) Funny (not) how "real world" data takes so long to "come out"! Here is a recent publication (2018), all about "Viekirax" (ombitasvir/paritaprevir/ritonavir) and "Exviera" (dasabuvir) - also known as "OPrD" (similar to later and further formulations named Viekira Pak and then Viekira XR).B...	Canuck	2	2066	Mar 7, 2018 by Tig
	Hep C crosses the brain barrier (Preview) https://www.hepmag.com/article/HCV-Brain-Endothelium-21818-1287637502	skewedButNotBroken	4	2469	Jan 24, 2018 by LamontCranston
	Harvoni SVR and then case of psoriasis remission (Preview) Published in Gastroenterology - News · January 18, 2018Psoriasis Remission Described After Hepatitis C Virus TreatmentCase report: After initiation of ledipasvir-sofosbuvir, HCV RNA decreased, and skin lesions improvedHealthDay WEDNESDAY, Jan. 17, 2018 (HealthDay News) -- A case of...	Canuck	3	2276	Jan 22, 2018 by Canuck
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