The same can be said for cancer treatment and survival rates, minimally invasive surgeries (orthoscopic), and other medical advances. Unfortunately, with better meds and proceedures, there is going to be higher costs and insurance headaches. I don't think Hep C will ever get the noteriety as other illnesses.
JoAnneh said
Nov 22, 2012
Yes, this drugs are barbaric but they Have a change to save us! I have cirrhosis And thankful med is working. I can't wait to feel better. I do hope future generations have easier time. JoAnne
mallani said
Nov 22, 2012
Hi Mark, in 10 years we can look at the early protease inhibitors as 'the beginning of the end' for HCV. Incivek and Victrelis are remarkable advances, being the first DAA's. To be able to block an enzyme site on a virus that can't be cultured is a remarkable feat. It is just unfortunate that both drugs have bad Sx. This is because both drugs don't just block the HCV protease- they block other protease sites thoughout the body. The next generation protease inhibitors will be more selective in their action, and should be fairly free of Sx. Interferon has always had Sx as it is produced by the body and has a wide range of actions. To get rid of it, a combination of new DAA's will be needed to reduce the risk of RAV's. Riba may still be around in 10 years for certain groups of patients- although it's antiviral action is fairly weak ( and still not well understood). In 10 years, the drugs will be consolidated into one or two pills/ day. The high pill burden we currently suffer could have been reduced eg the 4 Vict. caps could have been compacted into 1. The Rx time will also be compressed into 6, 12 or maybe 24 weeks.(or even less).
Looking back in 10 years time, patients will shake their heads in wonder at what we put up with. I can't wait 10 years, so I'm happy to be on these 'barbaric' drugs.
Bills said
Nov 22, 2012
I like what your saying I guess this is like one of those necessary evils we have to deal with I'm at week 16 of this second round this time Inciveck I didn't do week 16 VL yet but I think I'm ok UND last one @ 12 If & When I clear SVR I don't want to see anymore Drs and hope I can hold my tongue about drug companies Well Have a nice Thanksgiving Bill S
marktrux said
Nov 21, 2012
I was just wondering how members and the medical community will look back on the current SOC's. Will we look back on them as the lifesavers they appear to be or will we look back on them as some form of barbaric medieval torture that was rushed into production to satisfy the stockholders of Big Pharma? Personally I'm glad to have had the oppertunity to rid myself of the evil inside, though sometimes it dosen't feel like it.
The same can be said for cancer treatment and survival rates, minimally invasive surgeries (orthoscopic), and other medical advances. Unfortunately, with better meds and proceedures, there is going to be higher costs and insurance headaches. I don't think Hep C will ever get the noteriety as other illnesses.
Have a change to save us! I have cirrhosis
And thankful med is working. I can't wait to feel better.
I do hope future generations have easier time.
JoAnne
Hi Mark, in 10 years we can look at the early protease inhibitors as 'the beginning of the end' for HCV. Incivek and Victrelis are remarkable advances, being the first DAA's. To be able to block an enzyme site on a virus that can't be cultured is a remarkable feat. It is just unfortunate that both drugs have bad Sx. This is because both drugs don't just block the HCV protease- they block other protease sites thoughout the body. The next generation protease inhibitors will be more selective in their action, and should be fairly free of Sx. Interferon has always had Sx as it is produced by the body and has a wide range of actions. To get rid of it, a combination of new DAA's will be needed to reduce the risk of RAV's. Riba may still be around in 10 years for certain groups of patients- although it's antiviral action is fairly weak ( and still not well understood). In 10 years, the drugs will be consolidated into one or two pills/ day. The high pill burden we currently suffer could have been reduced eg the 4 Vict. caps could have been compacted into 1. The Rx time will also be compressed into 6, 12 or maybe 24 weeks.(or even less).
Looking back in 10 years time, patients will shake their heads in wonder at what we put up with. I can't wait 10 years, so I'm happy to be on these 'barbaric' drugs.
I like what your saying
I guess this is like one of those necessary evils we have to deal with I'm at week 16 of this second round this time Inciveck I didn't do week 16 VL yet but I think I'm ok UND last one @ 12
If & When I clear SVR I don't want to see anymore Drs and hope I can hold my tongue about drug companies
Well Have a nice Thanksgiving
Bill S
I was just wondering how members and the medical community will look back on the current SOC's. Will we look back on them as the lifesavers they appear to be or will we look back on them as some form of barbaric medieval torture that was rushed into production to satisfy the stockholders of Big Pharma? Personally I'm glad to have had the oppertunity to rid myself of the evil inside, though sometimes it dosen't feel like it.