Hi Kathy, if you have failed treatment with the first generation protease inhibitors (PI's), you will had great trouble being accepted for a trial. Any trial using a second generation PI has previous Rx with Incivek or Victrelis listed as an exclusion. This is because of resistant mutations (RAV's). The only significant trial that does not use a PI is Gilead's (NS-5A and NS-5B blockers). Although this is a worldwide trial, places are very limited.
TazKat said
Dec 12, 2012
thanks teddytrout.. love the little pic.. lol i will try not to give up. am at stage 3 flirting with 4 as of 4 yrs ago. i hate the interferon & riba.l. just hate it!!! i reeally don't know if nurse pract from that office would even prescribe me anything. she became a bitch.. :)
TeddyTrout said
Dec 12, 2012
They are developing many new treatments and other protease inhibitors that attack this virus. They are developing treatments with out use interferon or ribavin . I wouldn't be to concerned at this point about it. You may be very receptive to the P.I. but a non-responder to interferon. So try not to put the cart before the horse, I would stay well focused in on how well this new treatment is going to be and keep a positive outlook going forward. Don't sweat the small stuff as it only leads to hair loss. Cheers
TazKat said
Dec 12, 2012
the protease inhibitor after 32 weeks of triple/combo treatment can i never ever do the protease inibitor ever again? if not what pipeline drugs do i need to track. i have been on riba/interferon twice & the the interferon/riba/incivik once.. lots of toxic crap put in my body.. thanks for any in\fo..
Hi Kathy, if you have failed treatment with the first generation protease inhibitors (PI's), you will had great trouble being accepted for a trial. Any trial using a second generation PI has previous Rx with Incivek or Victrelis listed as an exclusion. This is because of resistant mutations (RAV's). The only significant trial that does not use a PI is Gilead's (NS-5A and NS-5B blockers). Although this is a worldwide trial, places are very limited.
thanks teddytrout.. love the little pic.. lol i will try not to give up. am at stage 3 flirting with 4 as of 4 yrs ago. i hate the interferon & riba.l. just hate it!!! i reeally don't know if nurse pract from that office would even prescribe me anything. she became a bitch.. :)
the protease inhibitor after 32 weeks of triple/combo treatment can i never ever do the protease inibitor ever again? if not what pipeline drugs do i need to track. i have been on riba/interferon twice & the the interferon/riba/incivik once.. lots of toxic crap put in my body.. thanks for any in\fo..