That's great news Zlick! Your persistence has paid off. Let us know when you get started on the meds and about your progress. Good luck!

Hey Zlick,

Awesome buddy!! Well deserved too! Please keep us informed of your progress. We all have an interest in your success and want to follow you through. I'm so glad that you're finally getting this opportunity. You fought long and hard for this and the one thing that is different this time, will be the three big letters after you're done, SVR.... How sweet that will be!

Hi Z,

Glad to hear its finally happening for you.

cheers

Hi Zlikster,

Best of luck buddy. It's been a long search for you. I look forward to Undetectable results. Enjoy winter in Bosnia. Cheers.

Hey folks!

i am about to obtain Sof+Dac via Australia, so in cca 3 weeks i am going to give it a go and share my experience with DAAs.

@Max keeps us posetd how it goes with Dac+Sof :)

@Robert ugh Peg, but since you are F4 i guess you can't avoid it and it's only 12 weeks, tho as i seen guindlines for cirrhotics it's also option with Sof+Dac+Riba for 24weeks?  VL <15 @ week 4? Thats great! :)

@GypsySoul Hope you stay UND :) hey, after few years, maybe you will miss some Riba cranky overemotinal mood ;)

cheers!

Hellow fellow 3-fighters.  Wanted to report in that I"m on shot #5, my LFT"s are all droping fast, load has gone from 5million to <15.  SX  not to bad!    Hope everyone is doing well.  RC

Thanks ,TIG for your wishes ! 

And what about complexities of languages : i also use the browser translater and we have joke on our comedy TV

https://rutube.ru/video/903cac240ead590776c8c938c0246bdf/?autoStart=true&bmstart=10

Welcome Zlikster!!

I am in week 17 of the 24 week tx. Overall not too many side effects here...just achy joints in the evening,

a few days when I'm emotional, and easily winded. But really manageable and I consider myself really lucky.

My last dose of the Riba/Sovaldi will be December 12th and so far my VL's have come back undetected...

hope it continues after tx.

Any future tx planned?

Hi Ell,

If you're just learning English, congratulations, you're doing very well. I have a nephew that is from Russia and I'm amazed at his ability to speak, write and communicate using both simultaneously! They are both very complex languages. Keep it up!

Stopping smoking is one of the best things you can do for your health. It's also one of the most difficult to stop. Once you set your mind to it and get past the first week, you're ahead of the game. I found one of the hard things to do was what to do with my hands and reaching for that smoke after eating. When I was drinking alcohol, I chain smoked. Once you rid yourself of this virus and quit smoking, your body won't know what to do with all of the new found health!

I can't say what will happen regarding your heart, only your doctor knows for sure. But I have to believe that your new found health will have a very positive impact on everything. Stick with it and I guarantee you healthier days ahead!

Hi all! I'm already on14 week.I had heart problems. They strongly expressed when Smoking tobacco. Found the problem with the left heart ventricle . I smoked for 20 years.Now stopped Smoking and consume nicotine oral anxiety became less.But I  began to worry about the future, the stateof my heart. I have already reduced the ribavirin to 800 mg.. Interesting : reversible if cardiac symptoms after therapy ? And what drugs can be support the heart ?

-- Edited by ell on Thursday 22nd of October 2015 09:01:35 PM

Hi Max, Nice to have a fellow type 3 to go through treatment with. (same time period) I started treatment last thursday, sof-riba-peg for 12 weeks.  My second shot is today at 3 pm.  The first shot was un eventful, It sounds like you got a lot of help with your meds, thats great. Your treatment should go well. The sof-dac is the way to go if non cirrhotic.Post your LFT"s as you go through treatment, looking forward to seeing your numbers drop fast!!  There should not be any  bad S/X from the combo you will take.   Best of luck, I will be watching your results.  

RC

Good deal Max. I'm glad you're getting the show on the road. I too will be following your progress and wishing you well. Onward to SVR!

You definitely have our support and are wishing you all the luck this message can hold! Just keep us updated with anything you hear, tests taken and questions you might have. I'm anxious to follow your progress on this protocol. Good luck!

Yeah Tig, 1% tinnitus as sidefx from Peg my arse. From the stories from folks on this forum it might be more into 10% area. Problem is that not all people are reporting it to their docs as sidefx.

Robert, do not do peg if u have tinnitus precondition. In my case, if i knew that i will get this type of tinnitus, i would never do peg. Only would opt in in case of really bad situation with liver!

Omar, don't worry :) U might get a bit cranky and emotional from Riba (with short breathness from low Hgb) few headaches, but thats all...Sofosbuvir is pretty safe. PegInterferon on other hand is carpet bombing. Let us know how it goes with treatment! I am trying to get my hands on some Sofosbuvir love (and maybe some Daclatasvir) and will go on same tx as u.

cheers!

I'm not a GT 3, but have discussed tinnitus with Zlickster many times before. i also spent decades in the industrial arts, lots of noise as well. I have had issues with tinnitus for years but it wasn't too bad. Then I started my second round of treatment that included Victrelis. It was shortly after starting it, I noticed a severe increase in it. It has increased in pitch (deafening at times) and I noticed a new addition to it. I'm now experiencing a very loud rushing water noise accompanying the high pitch whine. At night I can barely stand it. A sound generator helps but only marginally. I'm convinced it's treatment related. Talked to an audiologist, tried high dollar hearing aids (no help) and have gotten more relief from the noise generator or leaving a TV on low when I can't take it. It has lead to a lot of sleepless nights.

I have always been around air tools,compressors,loud engines, Yep! I'm (was) a mechanic. So I have always had a humming in my ears, just figured it came with the job. I am however kinda worried about it geting worse if I do a Peg treatment. The GS-5816 will hopefuly be the answer for  F3-F4 type 3"s when added to Sof.    RC

Hi folks ;)

Jake, do tell me more. How on earth were u missdiagnosed with genotype? If i understood well, u are not treatment naive and now you are on Sof+Dac+Riba for 24w cause of HIV+ and F4?


Hi Rob,

I did Peg+Riba for 23weeks (missed one shot). Was UND from 8th week, relapsed somewhere in first 2 months post tx. Pre tx I had a really mild tinnitus, on both ears (really high pitched one), professional one (loud music exposure), but from first peg injection or 2nd i got elevated that one and a new one, tonal just on left ear. Pre tx, i used to sleep without any tinnitus masking devices, maybe few times per year i would have to turn on fan or something to mask it, now i can't sleep a single day without a fan or a noise from loudspeaker (good thing my gf got used to it).

As i could see latest guidlines for GT3 regarding all oral tx is Sofosbuvir+Daclatasvir (without Riba since seems it doesn't have much impact) 12-24weeks.

Keeping still fingers crossed for Gilead's GS-5816, it might be even better than Daclatasvir.

cheers

Great idea !!  As a fellow Type 3, I think we 3"s need to share our experience in a common thread . Having said that, I don"t want to exclude any other types from chiming in on your thread.I welcome all the input I can get.

Zlikster, I was wondering how long you did Peg-Riba? in 2013.   You said you got Tinnitus from that treatment.     RC

Hi Zlikster,

You`re welcome to create a genotypeist sect just as you don`t start abducting anyone! 

Hope you`re doing ok, good idea for a thread.

Hello, Jake here.  10 years after being diagnosed with genotype 2a, and 2 failed peg riba treatments later, I just found out it is not genotype 2 I have, but 3.  So, my treatment with sobufir daclatasvir and riba is extended from16 to 24 weeks.  I am not oving the articles I am reading regarding cure rates for this genotype especially being treatment naive, having cirrhosis 4 and being HIV+. We shall see how this works out.  Cheers JB

I am not making a genotypeist sect or anything just wonder if anyone from GT 3 folks is willing to share their stories regarding therapy and GT3 particular conditions like liver steatosis. I am also curios has anyone shorten their therapy or reduced Ribavirin dosage cause of RVR?

thanks