Sofosbuvir + ribavirin is safe and effective for HCV recurrence after liver transplantation
Cinnamon Girl said
May 13, 2014
"An interferon-free combination of sofosbuvir (Sovaldi) plus ribavirin taken for up to 24 weeks led to sustained virological response in 70% of liver transplant recipients with hepatitis C virus (HCV) recurrence, according to a poster presented at the 49th annual meeting of the European Association for the Study of the Liver (EASL) held recently in London."
"Hepatitis C virus almost always re-infects the new liver after a transplant. This can lead to rapid fibrosis progression with an increased risk of graft loss and life-threatening complications. Interferon - the former standard of care for hepatitis C - is often poorly tolerated and not very effective for people with advanced liver disease. Sofosbuvir is a promising option because it is well tolerated and does not interact with immunosuppressant drugs used to prevent organ rejection."
"An interferon-free combination of sofosbuvir (Sovaldi) plus ribavirin taken for up to 24 weeks led to sustained virological response in 70% of liver transplant recipients with hepatitis C virus (HCV) recurrence, according to a poster presented at the 49th annual meeting of the European Association for the Study of the Liver (EASL) held recently in London."
"Hepatitis C virus almost always re-infects the new liver after a transplant. This can lead to rapid fibrosis progression with an increased risk of graft loss and life-threatening complications. Interferon - the former standard of care for hepatitis C - is often poorly tolerated and not very effective for people with advanced liver disease. Sofosbuvir is a promising option because it is well tolerated and does not interact with immunosuppressant drugs used to prevent organ rejection."
Full article...
http://www.aidsmap.com/Sofosbuvir-ribavirin-is-safe-and-effective-for-HCV-recurrence-after-liver-transplantation/page/2851593/