Can someone please "Clarify what would cause a RELAPSE after clearing the virus?"
Femapples said
May 31, 2015
Are you discussing the relapse rate for naïve treatment? I believe it's 1 or 2% more for people who have been previously treated.
F.
hepCFREEwanab said
May 30, 2015
We went to see Angelo's Hepatologst and he wants Blood test done after 4 weeks EOT.
He said that if after 4 weeks he's still UND that is a pretty good indication that he is in 98% group that achieves SVR! The other 2 % are the people that although have been UND for a while, meaning that the virus has cleared the blood, any trace left behind in the liver could trigger a relapse!
So waiting for 12 weeks to check after EOT how well the treatment really went, it's a bit much!
So, he finished on May 10th, next blood work after 4 weeks on June 8, then finally at 12 weeks which by coincidence is his Birthday!
Mena
basser said
May 30, 2015
think the only chance of the virus surfacing again after getting svr is reinfecting.as i dont do anything that would cause reinfecting myself cant see any reason for a relapse.but is early days and there is still a lot of confusion around the whole issue of hep c.all i can do is look after myself with a gd diet/ exercise and sleep.am still recovering from effects of meds and damage done from having the virus for about 25yrs.thts enough to be getting on with for now. best of health to you all william
hepCFREEwanab said
May 28, 2015
Tig56 wrote:
Hi Mena,
The documented rate of relapse following SVR is <=1%. The feeling is that may even improve over time but nothing concrete. So there is a remote chance of relapse but it's so rare it isn't discussed. The feeling is once you achieve SVR, you're done. Re infection is different and is thought to be far more common than a relapse from the original infection.
How's Angelo? I hope you are both doing well.
This is exactly what I thought. Thanks Tig.
Angelo is doing pretty well , finished Harvoni on May 10 . Up to that day all blood results showed UND.
Tomorrow he has an appointment with his regular Hepatologist and on June 17th he goes back to Mt. Sinai for a follow up MRI. to see if hopefully the tumors have shrunk even more.
Will post any updates.
Mena
Tig said
May 28, 2015
Hi Mena,
The documented rate of relapse following SVR is <=1%. The feeling is that may even improve over time but nothing concrete. So there is a remote chance of relapse but it's so rare it isn't discussed. The feeling is once you achieve SVR, you're done. Re infection is different and is thought to be far more common than a relapse from the original infection.
How's Angelo? I hope you are both doing well.
Matt Chris said
May 28, 2015
Hey Mena
How are you two doing these days? Are you currently in treatment or have you finished?
Sometimes HCV members/patients received test results during treatment or at the end of their treatment to see if the virus is detectable or NON-Detectable. From a results standpoint if this comes back as not-detectable this a very good thing, but not the same as clearing the virus or SVR-12.
Most Doctors and HCV specialist consider SVR-12 (12 weeks after treatment ends still undetectable) or longer SVR-24 as a cure or clearing the virus from the body to the point where your own immune system can handle any minute amount that may remain.
If you attain SVR-12 / SVR-24 status the odds are about 1% or 2% that you could relapse from the original infection, if you for some crazy reason re-infected yourself via blood contamination or IV drug use you could end up with a new case of HCV.
hope this clear up some questions.
matt
hepCFREEwanab said
May 28, 2015
It is my understanding that the only way to relapse after clearing the virus, would be if that person were to be "Reinfected again"!
Are you discussing the relapse rate for naïve treatment? I believe it's 1 or 2% more for people who have been previously treated.
F.
We went to see Angelo's Hepatologst and he wants Blood test done after 4 weeks EOT.
He said that if after 4 weeks he's still UND that is a pretty good indication that he is in 98% group that achieves SVR! The other 2 % are the people that although have been UND for a while, meaning that the virus has cleared the blood, any trace left behind in the liver could trigger a relapse!
So waiting for 12 weeks to check after EOT how well the treatment really went, it's a bit much!
So, he finished on May 10th, next blood work after 4 weeks on June 8, then finally at 12 weeks which by coincidence is his Birthday!
Mena
think the only chance of the virus surfacing again after getting svr is reinfecting.as i dont do anything that would cause reinfecting myself cant see any reason for a relapse.but is early days and there is still a lot of confusion around the whole issue of hep c.all i can do is look after myself with a gd diet/ exercise and sleep.am still recovering from effects of meds and damage done from having the virus for about 25yrs.thts enough to be getting on with for now. best of health to you all william
This is exactly what I thought. Thanks Tig.
Angelo is doing pretty well , finished Harvoni on May 10 . Up to that day all blood results showed UND.
Tomorrow he has an appointment with his regular Hepatologist and on June 17th he goes back to Mt. Sinai for a follow up MRI. to see if hopefully the tumors have shrunk even more.
Will post any updates.
Mena
Hi Mena,
The documented rate of relapse following SVR is <=1%. The feeling is that may even improve over time but nothing concrete. So there is a remote chance of relapse but it's so rare it isn't discussed. The feeling is once you achieve SVR, you're done. Re infection is different and is thought to be far more common than a relapse from the original infection.
How's Angelo? I hope you are both doing well.
Hey Mena
How are you two doing these days? Are you currently in treatment or have you finished?
Sometimes HCV members/patients received test results during treatment or at the end of their treatment to see if the virus is detectable or NON-Detectable. From a results standpoint if this comes back as not-detectable this a very good thing, but not the same as clearing the virus or SVR-12.
Most Doctors and HCV specialist consider SVR-12 (12 weeks after treatment ends still undetectable) or longer SVR-24 as a cure or clearing the virus from the body to the point where your own immune system can handle any minute amount that may remain.
If you attain SVR-12 / SVR-24 status the odds are about 1% or 2% that you could relapse from the original infection, if you for some crazy reason re-infected yourself via blood contamination or IV drug use you could end up with a new case of HCV.
hope this clear up some questions.
matt
It is my understanding that the only way to relapse after clearing the virus, would be if that person were to be "Reinfected again"!
Am I wrong?
Mena