247, as a fellow type 3, and after failing treatment with sof-riba, I will be watching this trial and your results. Please keep us posted. There is no advantage of being a type 3 because we seem to be the hardest to treat,and if you add cirrhosis to the mess you deffinatley want riba. When I was diagnosed as a 3 in 89 or 90 ??I was told that was the best one to have and the easiest to treat. That was then, thay had just started geno typing hep c. Back in the early days (late 80"s to early 90"s) they just called it non a non b I thought i had lucked out with the type 3 diag. I even put off treatment because they said i had the easy one to treat. But to be honest about it I just did not want to have the flu for 48 months and was told I could wait for easyer treatments and that riba was just about to be unvailed and was the answer for better cure rates. Type 3"s dont show well in trial results so we kinda have been put at the back of the bus. But now that 1a and 1b have such a good svr , they will start more trials on us 3"s. hang in there!! RC
247kath said
Jun 25, 2015
Hi All
Yes that is the trial. i guess there is an advantage to being a less common genotype!! There is room for 100 people across Canada for this trial and it looks like they're still recruiting.
Cinnamon Girl said
Jun 25, 2015
Hi Bill,
As it stands at the moment Harvoni is only approved for treating Gen 1 and Kathy`s trial is for people with Gen 3. Gen 3`s don`t tend to respond as well to the new DAA drugs unless ribavirin is added to increase the success rates. So this trial will provide very useful data for possible future treatments with Harvon for those with Gen 3.
Here`s a link to the trial I think she is doing...
That sounds like good a Trial Harvoni alone is winner. Adding Ribavirin is insurance. many people here have done Riba. It sucks but it's not the worst of the drugs used.
I'll go out on limb and ask something for the more knowledgeable people.
Basing it on a pattern I see Do you think this trial is really testing the effectiveness of using Riba or not? My Doc said he felt there was not much difference in results for Harvoni with or without Ribavirin.
I am not knocking this trial I would have done it in heartbeat before Harvoni was released I was begging for something like this.
Another Plus Kathy is trials are Free ( most times ) not to mention when on a trial the docs are watching every move so you get best of care they treat you special. It's also good your NOT in a Blind Trail ( when they don't tell you the viral load and very little all around). If you've seenVL then it's NOT Blind. I was a Lab rat once too.
You'll do fine Kathy you have a winning combo
BillS
Matt Chris said
Jun 24, 2015
Hello Kathy
Welcome to the forum from me as well, you have found a good place with members who have great insight on all things HCV. Hope you have good results during and after your trial.
matt
wmlj1960 said
Jun 24, 2015
Hi Kathy.
I would also like to welcome you to this very helpful forum. When I first sought treatment for my Hep C it was suggested that I get educated and get involved. This forum is, for the most part, where I learned to do that and I'm glad I did. So make yourself at home and join us all in our journey to beat the Hep C dragon.
Cinnamon Girl said
Jun 24, 2015
Hi Kathy, that's brilliant news! So pleased you've got off to such a great start to your treatment, very pleased for you!
Tig said
Jun 24, 2015
Outstanding Kathy! You will certainly be undetected following your next test. You are responding exactly the way we like to see and better than many, considering it has only been one week. Congratulations is in order! You've got the Dragon on the run already, woot!!!!
247kath said
Jun 24, 2015
Thank you for the welcomeWas away for a few days. Weekly check in yesterday at hospital and viral load had been over800,000 at start and after one week had dropped to 31. OMG unbelievable! The emotion that came over me brought me to tears. After discovering that I had HCV 20 years ago and now to realize it could be gone was overwhelming. I had never realized how much it pressed on my mind until that moment. Grateful beyond belief.
robertsamx said
Jun 18, 2015
found the trial you are on, that should do it for you. Congratulations on geting into that one. RC
robertsamx said
Jun 18, 2015
welcome 247 Harvoni and riba are a strong T/X .wishing you the best of luck . I was wondering what trial youy were on and would like to know more about the trial. This forum has a lot of answeres. RC
coolheat said
Jun 18, 2015
Glad you're here, seems no matter what, all or any participation is helpful to everyone. CH Look forward to hearing your successes.
247kath said
Jun 18, 2015
Thank you! New to using a forum and kind of private person so hope I can add a bit to it.
Tig said
Jun 18, 2015
Hi Kathy,
Welcome to the forum, I'm glad you're here! You will meet a lot of good people and everyone is always willing to help. You will be hearing from them soon and if you need anything, let us know.
You're on a very effective protocol and 12 weeks of it have proven very effective for all fortunate to get it. What is the name of your trial? Have you treated before? There will be some questions and any information you can share will help us provide better informed opinions and suggestions, should you desire them.
If you haven't checked out our Forum Information and Knowledge Base sections, you will find a lot of helpful information included there. I recommend adding your treatment info to your signature line, like mine if you would like. It's easier than having to repeat yourself when asked during various conversations. You can find your signature section on your profile page and instructions. There are instructions on the Forum Info page (3rd box down). If you have any questions you need answered, don't hesitate to ask. Good luck!
247kath said
Jun 18, 2015
New here. On Clinical trial started 6/9/15 Harvoni and ribavirin for 12 weeks.
247, as a fellow type 3, and after failing treatment with sof-riba, I will be watching this trial and your results. Please keep us posted. There is no advantage of being a type 3 because we seem to be the hardest to treat,and if you add cirrhosis to the mess you deffinatley want riba. When I was diagnosed as a 3 in 89 or 90 ??I was told that was the best one to have and the easiest to treat. That was then, thay had just started geno typing hep c. Back in the early days (late 80"s to early 90"s) they just called it non a non b I thought i had lucked out with the type 3 diag. I even put off treatment because they said i had the easy one to treat. But to be honest about it I just did not want to have the flu for 48 months and was told I could wait for easyer treatments and that riba was just about to be unvailed and was the answer for better cure rates. Type 3"s dont show well in trial results so we kinda have been put at the back of the bus. But now that 1a and 1b have such a good svr , they will start more trials on us 3"s. hang in there!! RC
Hi All
Yes that is the trial. i guess there is an advantage to being a less common genotype!! There is room for 100 people across Canada for this trial and it looks like they're still recruiting.
Hi Bill,
As it stands at the moment Harvoni is only approved for treating Gen 1 and Kathy`s trial is for people with Gen 3. Gen 3`s don`t tend to respond as well to the new DAA drugs unless ribavirin is added to increase the success rates. So this trial will provide very useful data for possible future treatments with Harvon for those with Gen 3.
Here`s a link to the trial I think she is doing...
https://clinicaltrials.gov/ct2/show/NCT02413593?term=gilead+harvoni+and+ribavirin&rank=2
Hi Kathy
That sounds like good a Trial Harvoni alone is winner. Adding Ribavirin is insurance. many people here have done Riba. It sucks but it's not the worst of the drugs used.
I'll go out on limb and ask something for the more knowledgeable people.
Basing it on a pattern I see Do you think this trial is really testing the effectiveness of using Riba or not? My Doc said he felt there was not much difference in results for Harvoni with or without Ribavirin.
I am not knocking this trial I would have done it in heartbeat before Harvoni was released I was begging for something like this.
Another Plus Kathy is trials are Free ( most times ) not to mention when on a trial the docs are watching every move so you get best of care they treat you special. It's also good your NOT in a Blind Trail ( when they don't tell you the viral load and very little all around). If you've seenVL then it's NOT Blind. I was a Lab rat once too.
You'll do fine Kathy you have a winning combo
BillS
Hello Kathy
Welcome to the forum from me as well, you have found a good place with members who have great insight on all things HCV. Hope you have good results during and after your trial.
matt
Hi Kathy.
I would also like to welcome you to this very helpful forum. When I first sought treatment for my Hep C it was suggested that I get educated and get involved. This forum is, for the most part, where I learned to do that and I'm glad I did. So make yourself at home and join us all in our journey to beat the Hep C dragon.
Hi Kathy, that's brilliant news! So pleased you've got off to such a great start to your treatment, very pleased for you!
Outstanding Kathy! You will certainly be undetected following your next test. You are responding exactly the way we like to see and better than many, considering it has only been one week. Congratulations is in order! You've got the Dragon on the run already, woot!!!!
Thank you for the welcomeWas away for a few days. Weekly check in yesterday at hospital and viral load had been over800,000 at start and after one week had dropped to 31. OMG unbelievable! The emotion that came over me brought me to tears. After discovering that I had HCV 20 years ago and now to realize it could be gone was overwhelming. I had never realized how much it pressed on my mind until that moment. Grateful beyond belief.
found the trial you are on, that should do it for you. Congratulations on geting into that one. RC
welcome 247 Harvoni and riba are a strong T/X .wishing you the best of luck . I was wondering what trial youy were on and would like to know more about the trial. This forum has a lot of answeres. RC
Glad you're here, seems no matter what, all or any participation is helpful to everyone.
CH Look forward to hearing your successes.
Thank you! New to using a forum and kind of private person so hope I can add a bit to it.
Hi Kathy,
Welcome to the forum, I'm glad you're here! You will meet a lot of good people and everyone is always willing to help. You will be hearing from them soon and if you need anything, let us know.
You're on a very effective protocol and 12 weeks of it have proven very effective for all fortunate to get it. What is the name of your trial? Have you treated before? There will be some questions and any information you can share will help us provide better informed opinions and suggestions, should you desire them.
If you haven't checked out our Forum Information and Knowledge Base sections, you will find a lot of helpful information included there. I recommend adding your treatment info to your signature line, like mine if you would like. It's easier than having to repeat yourself when asked during various conversations. You can find your signature section on your profile page and instructions. There are instructions on the Forum Info page (3rd box down). If you have any questions you need answered, don't hesitate to ask. Good luck!
New here. On Clinical trial started 6/9/15 Harvoni and ribavirin for 12 weeks.