the VLs can vary drastically. When I was deciding whether or not to do the old treatment, the Dr. ordered VLs and it was 7 million, then a few months later it was 3 million. (I thought it was because of meditation )
I had it tested a few years later and it was over 7 million, then just last year before this treatment it was only 7K.
Now it's UND.
Alison
Pablito said
Sep 6, 2016
Hi Greg
RAVs are resistance associated mutations, bad copies of the virus that don't respond to the enzyme blockers in the DAAs. They tend to lie behind most treatment failures, but they are rarely checked for in routine clinical practice. I wouldn't worry about them though as sofosbuvir, which you'll be getting in Harvoni, is very resistant to RAVs.
Pablo
Greg said
Sep 6, 2016
Pablito wrote:
Hi Greg
VLs vary hugely so I wouldn't worry too much. They do tend to go up after a treatment that didn't work but the new DAAs are so potent - a 2 log drop after once dose - that whilst it's reassuring to have a low VL and it might take a little longer to achieve UND than with a low VL you will go UND during treatment.
The real enemies are RAVs. Did they do RAV testing after your last treatment?
Best of luck.
Pablo
Hi Pablo Thanks for your quick reply, and your reassuring words. I'm unfamiliar with RAV, just had a quick google and no they didn't do that test after TX. But hopefully will be touching base with my specialist today and will discuss that subject.
Love and Light, Greg
Pablito said
Sep 6, 2016
Hi Greg
VLs vary hugely so I wouldn't worry too much. They do tend to go up after a treatment that didn't work but the new DAAs are so potent - a 2 log drop after once dose - that whilst it's reassuring to have a low VL and it might take a little longer to achieve UND than with a low VL you will go UND during treatment.
The real enemies are RAVs. Did they do RAV testing after your last treatment?
Best of luck.
Pablo
Greg said
Sep 6, 2016
Thanks everyone once again for your support,
I have a quick question and must admit I am a bit concerned. Back in 2011 pre TX my VL was around 2Mil and went down to a couple of thousand. Now my latest VL is upwards of 7Mil. I know this is a question for my specialist who will get a call today hopefully. But I was wondering as I was a non-responder did the TX trigger off some sort of renewed rapid replication mechanism, or might other factors be in play? Look forward to your replies.
Love and Light, Greg
Phoenix17 said
Sep 5, 2016
Hi Greg.
I wasn't here when you first started, but I am really happy for you to be able to get rid of this awful virus once and for all!
Have a great time with your granddaughter! Those are special moments.
Liz
Cinnamon Girl said
Sep 5, 2016
Hi again, Greg!
Your little granddaughter`s birthday party is your first priority of course, and then you can get down to the serious business of taking on that Dragon again, and this time it will be for good!
I`m so thrilled for you getting Harvoni at last, you`ve been waiting around for long enough and you`ll soon be on your way to SVR, my friend!!
Oh, and happy birthday wishes to your granddaughter, have the best fun ever!!!
RAGDOLL said
Sep 5, 2016
Hi Greg, welcome back to the forum. So glad to hear about your retreatment option. These new drugs are so much better. Looking forward to you slaying the dragon this time around. Best Wishes! Chris
Tig said
Sep 5, 2016
Hi Greg,
You're going to be amazed at the effectiveness of these drugs. So completely different from the things we experienced with the old SOC's. You are blessed with a PBS that provides them, too.
Enjoy that special day with your grand daughter . Some days are more special than others and that is one of them! Save us a piece of cake
Good luck, Mate!!
Observer said
Sep 5, 2016
Hi Greg,
I am so glad you are getting a re-match with the dragon. This time will be a whole lot different for you.
my old Drs. pushed me to try interferon, riba in early 2000's but I researched a bunch and I was too scared of what people were going through to try it.
Fast forward 15 years of research and have my daughter beg me to get the new drugs and I am now SVR. Our healthcare system would only pay for 8 weeks of harvoni, but my new Dr was worried with my cirrhosis I'd better do 12 weeks so I did the holkira pak with the riba experience. but all good now.
Anyhoo, I look forward to seeing your numbers drop this autumn. Have fun at your granddaughters birthday
Alison
Greg said
Sep 5, 2016
Hi Cauck,
Thanks for saying G'day, yes I forgot to mention that I will be on Harvoni for 12 weeks at this stage, hopefully that won't change. I could start now but have my granddaughter's birthday party this weekend and want that to be special for her then I'll tackle this beastie the following day.
Cheers mate,
Greg
Canuck said
Sep 5, 2016
Hi Greg,
Glad to meet you! Glad for your new doc and the new drugs. We will all be happy to see you free. Is it Harvoni for you? And how long?
Happy 11th! C.
Greg said
Sep 5, 2016
Hi Everyone,
So good to see so many old friends here and new ones too, thank you once again for your kind words and encouragement. Iris the first dance is mine lovely lady. Malcolm we are so lucky in this country to have this provided to us on the PBS, just amazing and thanks for thinking of me mate. My son and I are becoming members at the Gabba later this year so you might get an invite.
My new specialist was a complete opposite to my old one and a breath of fresh air who was on the ball with everything, within 30 mins I had my scripts in hand. I have some basic results below more to follow so stay tuned.
HCV Vir Load is 7.39 Mil
Viral Log is 6.9
That's all I have at the moment, will be having my Ultrasound etc on the 20th of this month so will post the results as well. I will start TX next Sunday the 11th. Just wanted to mention a grateful thank you to Jime, one of our former members who was one of the first people to trail these wonderful new drugs and thanks to him, myself and many others are able to free ourselves of this horrible virus. I know you will be in there with me mate as the re-match begins. Like last time hitting below the belt is allowed.
Love and Light to all,
Greg
Sydhanrahan said
Aug 25, 2016
Hi Greg,
i went back and had a look at some of those old Intreferon/RIBA posts and was filled with so much respect for what you all went through - most for 48 weeks!!!
With the new DAAs this rematch will be over before you realise it's started.
Syd
wmlj1960 said
Aug 25, 2016
You're right Greg - that "dragon is going down" this time and compared to your last time you will barely know you are in a fight. Welcome back!
Iris Dragonfly said
Aug 24, 2016
Hey there sweetie! You didn't think you could sneak in here without a big hug from me! This is excellent news! Much congratulations to you. I hear the side effects are much less with the newer treatments. Do you know which one is your option yet? Man, it's really good to see you. We should go spin some tunes on the juke box and dance! Just like the good ol days !....
Welcome to the final battle, my far away friend , many blessings on your quest!
Iris
mallani said
Aug 24, 2016
Hi Greg,
Mate, it's good to hear from you. I thought you should get on the Australian PBS drugs.
My Hepatologist in Brisbane is working though all his old non-responders. ALL have been Undetected after 4 weeks.
I guess you'll be on Harvoni so keep us posted. You've got this.
Cheers.
Shadowfax said
Jul 23, 2016
Welcome back Greg,
Although I was not here when you initially posted here, the forum as you say is great and the members and moderators are great. They help so many people get through treatment and everything leading up to it and after it.
New drugs as you know are here and very effective. This time is going to be a piece of cake I am sure.
Good luck and glad you will revisit this again.
SF
Greg said
Jul 15, 2016
Hi everyone and thanks for the lovely warm welcome, Feels great to be back, I can't wait to get started. Can't believe I said that after the last effort. Just wanted to thank you all for your kind words.
Love and Light, Greg
JimmyK said
Jul 15, 2016
Man I love a good Re-Match! Seems like there is always some refinement to the first attempt.
Welcome back Home!
JimmyK
Cheddy said
Jul 15, 2016
Yeah Greg! Down dragon coming up!!!
Loopy Lisa said
Jul 15, 2016
Hi Greg,
You'll think this is a picnic in the park compared to the horror 48 week nightmare. I'm glad you'll be on the new treatment train, the success rates are amazing and although you'll have probably some sides, they'll be nothing to what you previously endured.
Looking forward to hearing u kick its ass to timbuckto!
wendyo said
Jul 15, 2016
Hi Greg and welcome back.
I failed the same treatment back in the day and had success with Harvoni. Here's to your new dragon slaying and much success.
Yes, this site and the family here is a blessing.
wendy
Cinnamon Girl said
Jul 15, 2016
Hello Greg!
Great to see your news, my friend.. welcome back! I remember what you went through last time around and thank goodness you won`t have to go through that again. These new DAA treatments are a vast improvement on what people used to have to endure, and this time you`ll have a new and hopefully much more competent doctor in your corner!
Keep us posted...
Linuxter said
Jul 14, 2016
Hi Greg,
And welcome back, glad you are able to revisit Treatment, these new meds are extremely effective as I'm sure you well know.
Indeed this site has helped us one and all, it's a true pleasure to see you here now.
I'm sure Tig and others will be along shortly to welcome you back. We'll be here for the whole train ride, it's nice that you are well on your way to, as you say, plan an attack. We have an armory full of knowledge about us here, let us know if we can point you in any particular direction.
Keep us posted on how it's all going or just drop in any time to catch up on friends, folks and freedom HCV-Freedom that is, LOL
Dave (aka Linux)
Greg said
Jul 14, 2016
Hi Everyone, It's been a number of years since I last posted, and a lot of great and wonderful things have happened to me since then. Now it's time for a re-match with my particular Dragon I am a non-responder finished TX back in 2011. I have a new Doctor the last one retired, (no great loss....a long story don't want to go there lol, if you must it's in my blog.) so armed with a new Doctor and the new Meds I like my chances of beating this bugger this time around. I have an appointment on the 18th of August so hopefully will have a plan of attack and more news. I can't begin to tell you all how much this site and it's wonderful and very beautiful people helped me during TX last time. This Dragon is going down!
Hi Alison,
Excellent thank you and congratulations.
Love and Light,
Greg
I echo Pablo,
the VLs can vary drastically. When I was deciding whether or not to do the old treatment, the Dr. ordered VLs and it was 7 million, then a few months later it was 3 million. (I thought it was because of meditation
)
I had it tested a few years later and it was over 7 million, then just last year before this treatment it was only 7K.
Now it's UND.
Alison
Hi Greg
RAVs are resistance associated mutations, bad copies of the virus that don't respond to the enzyme blockers in the DAAs. They tend to lie behind most treatment failures, but they are rarely checked for in routine clinical practice. I wouldn't worry about them though as sofosbuvir, which you'll be getting in Harvoni, is very resistant to RAVs.
Pablo
Hi Pablo
I'm unfamiliar with RAV, just had a quick google and no they didn't do that test after TX. But hopefully will be touching base with my specialist today and will discuss that subject.
Thanks for your quick reply, and your reassuring words.
Love and Light,
Greg
Hi Greg
VLs vary hugely so I wouldn't worry too much. They do tend to go up after a treatment that didn't work but the new DAAs are so potent - a 2 log drop after once dose - that whilst it's reassuring to have a low VL and it might take a little longer to achieve UND than with a low VL you will go UND during treatment.
The real enemies are RAVs. Did they do RAV testing after your last treatment?
Best of luck.
Pablo
Thanks everyone once again for your support,
I have a quick question and must admit I am a bit concerned. Back in 2011 pre TX my VL was around 2Mil and went down to a couple of thousand. Now my latest VL is upwards of 7Mil. I know this is a question for my specialist who will get a call today hopefully. But I was wondering as I was a non-responder did the TX trigger off some sort of renewed rapid replication mechanism, or might other factors be in play? Look forward to your replies.
Love and Light,
Greg
Hi Greg.
I wasn't here when you first started, but I am really happy for you to be able to get rid of this awful virus once and for all!
Have a great time with your granddaughter! Those are special moments.
Liz
Hi again, Greg!
Your little granddaughter`s birthday party is your first priority of course, and then you can get down to the serious business of taking on that Dragon again, and this time it will be for good!
I`m so thrilled for you getting Harvoni at last, you`ve been waiting around for long enough and you`ll soon be on your way to SVR, my friend!!
Oh, and happy birthday wishes to your granddaughter, have the best fun ever!!!
Hi Greg, welcome back to the forum. So glad to hear about your retreatment option. These new drugs are so much better. Looking forward to you slaying the dragon this time around. Best Wishes! Chris
Hi Greg,
You're going to be amazed at the effectiveness of these drugs. So completely different from the things we experienced with the old SOC's. You are blessed with a PBS that provides them, too.
Enjoy that special day with your grand daughter
. Some days are more special than others and that is one of them! Save us a piece of cake 
Good luck, Mate!!
Hi Greg,
I am so glad you are getting a re-match with the dragon. This time will be a whole lot different for you.
my old Drs. pushed me to try interferon, riba in early 2000's but I researched a bunch and I was too scared of what people were going through to try it.
Fast forward 15 years of research and have my daughter beg me to get the new drugs and I am now SVR. Our healthcare system would only pay for 8 weeks of harvoni, but my new Dr was worried with my cirrhosis I'd better do 12 weeks so I did the holkira pak with the riba experience.
but all good now.
Anyhoo, I look forward to seeing your numbers drop this autumn. Have fun at your granddaughters birthday
Alison
Hi Cauck,
Thanks for saying G'day, yes I forgot to mention that I will be on Harvoni for 12 weeks at this stage, hopefully that won't change. I could start now but have my granddaughter's birthday party this weekend and want that to be special for her then I'll tackle this beastie the following day.
Cheers mate,
Greg
Hi Greg,
Glad to meet you! Glad for your new doc and the new drugs. We will all be happy to see you free. Is it Harvoni for you? And how long?
Happy 11th!
C.
Hi Everyone,
So good to see so many old friends here and new ones too, thank you once again for your kind words and encouragement. Iris the first dance is mine lovely lady.
Malcolm we are so lucky in this country to have this provided to us on the PBS, just amazing and thanks for thinking of me mate. My son and I are becoming members at the Gabba later this year so you might get an invite. 
My new specialist was a complete opposite to my old one and a breath of fresh air who was on the ball with everything, within 30 mins I had my scripts in hand.
I have some basic results below more to follow so stay tuned.
HCV Vir Load is 7.39 Mil
Viral Log is 6.9
That's all I have at the moment, will be having my Ultrasound etc on the 20th of this month so will post the results as well. I will start TX next Sunday the 11th. Just wanted to mention a grateful thank you to Jime, one of our former members who was one of the first people to trail these wonderful new drugs and thanks to him, myself and many others are able to free ourselves of this horrible virus. I know you will be in there with me mate as the re-match begins. Like last time hitting below the belt is allowed.
Love and Light to all,
Greg
Hi Greg,
i went back and had a look at some of those old Intreferon/RIBA posts and was filled with so much respect for what you all went through - most for 48 weeks!!!
With the new DAAs this rematch will be over before you realise it's started.
Syd
You're right Greg - that "dragon is going down" this time and compared to your last time you will barely know you are in a fight. Welcome back!
Hey there sweetie! You didn't think you could sneak in here without a big hug from me! This is excellent news! Much congratulations to you. I hear the side effects are much less with the newer treatments. Do you know which one is your option yet? Man, it's really good to see you. We should go spin some tunes on the juke box and dance! Just like the good ol days !....
Welcome to the final battle, my far away friend
, many blessings on your quest!
Iris
Hi Greg,
Mate, it's good to hear from you. I thought you should get on the Australian PBS drugs.
My Hepatologist in Brisbane is working though all his old non-responders. ALL have been Undetected after 4 weeks.
I guess you'll be on Harvoni so keep us posted. You've got this.
Cheers.
Welcome back Greg,
Although I was not here when you initially posted here, the forum as you say is great and the members and moderators are great. They help so many people get through treatment and everything leading up to it and after it.
New drugs as you know are here and very effective. This time is going to be a piece of cake I am sure.
Good luck and glad you will revisit this again.
SF
Hi everyone and thanks for the lovely warm welcome,
Feels great to be back, I can't wait to get started. Can't believe I said that after the last effort. Just wanted to thank you all for your kind words.
Love and Light,
Greg
Man I love a good Re-Match! Seems like there is always some refinement to the first attempt.
Welcome back Home!
JimmyK
Yeah Greg! Down dragon coming up!!!
Hi Greg,
You'll think this is a picnic in the park compared to the horror 48 week nightmare. I'm glad you'll be on the new treatment train, the success rates are amazing and although you'll have probably some sides, they'll be nothing to what you previously endured.
Looking forward to hearing u kick its ass to timbuckto!
Hi Greg and welcome back.
I failed the same treatment back in the day and had success with Harvoni. Here's to your new dragon slaying and much success.
Yes, this site and the family here is a blessing.
wendy
Hello Greg!
Great to see your news, my friend.. welcome back! I remember what you went through last time around and thank goodness you won`t have to go through that again. These new DAA treatments are a vast improvement on what people used to have to endure, and this time you`ll have a new and hopefully much more competent doctor in your corner!
Keep us posted...
Hi Greg,
And welcome back, glad you are able to revisit Treatment, these new meds are extremely effective as I'm sure you well know.
Indeed this site has helped us one and all, it's a true pleasure to see you here now.
I'm sure Tig and others will be along shortly to welcome you back. We'll be here for the whole train ride, it's nice that you are well on your way to, as you say, plan an attack. We have an armory full of knowledge about us here, let us know if we can point you in any particular direction.
Keep us posted on how it's all going or just drop in any time to catch up on friends, folks and freedom HCV-Freedom that is, LOL
Dave (aka Linux)
Hi Everyone,
It's been a number of years since I last posted, and a lot of great and wonderful things have happened to me since then. Now it's time for a re-match with my particular Dragon I am a non-responder finished TX back in 2011. I have a new Doctor the last one retired, (no great loss....a long story don't want to go there lol, if you must it's in my blog.) so armed with a new Doctor and the new Meds I like my chances of beating this bugger this time around. I have an appointment on the 18th of August so hopefully will have a plan of attack and more news.
I can't begin to tell you all how much this site and it's wonderful and very beautiful people helped me during TX last time. This Dragon is going down!
Love and Light,
Greg