Hey Gator,

Yes, keep hitting that water hard and 3-4 liters (gallon) per day is the target. It will turn you around and much of that nastiness will let up. It dehydrates you and if you start to feel a headache coming on, drink more water. You need to maintain a good diet as well, stay away from the junk. We should always concentrate on a good diet, but especially while you're on treatment. Give your body the nutrition and tools required to succeed in this battle against your Dragon. You'll feel much better as a result! Take a look at our Nutrition section for some good ideas.

We have people that take it in the morning or in the evening before bed. If you're one of those that feel some side effects during the day, you can take it at night, but you have to adjust your schedule with the approval of your doctor. Generally the rule has been to change to admin time by an hour each day or what is the latest recommendation by your healthcare team. 

Thank you for your response could you recommend athe best time of day to take it or is their a best time again thanks 

Gator,

Sorry you are not feeling well.  I remember feeling so thrilled about getting treatment and then feeling so poorly while I was on it.  It felt like a setback, but it wasn't.  During treatment I learned to wait out my feelings by keeping my eye on the goal.  Albeit counter intuitive, I had to quit listening to myself.  Chemistry was doing all the talking. I just had to put my head down and wait it out.  My instinct has always been to solve my problems, especially when it came discomfort.  This was the first time I had to remind myself that I actually was solving the problems.  The good news is that there is an end to it, and a grand reward for waiting it out. The other good news is that new treatments, I hear, are less devastating.

Enough said about water? I'll just add that long after treatment, water intake makes me feel healthier in general.  I can now tell the difference in my energy level and other minor discomforts if I don't keep up with 8-10 glasses per day.

Hang in there Gator.  You are solving a big problem.  I'm glad you've found a place here where you can get help, information, and empathy. 

Best to you,

Cheddy

Water? Well when I started treatment, I had 8 cases of water in my hall, each with 35 bottles in each. Nuff said?

Drink as much as you can, then drink a little more. It will make a world of difference.

SF

Double Yup! Water is an absolute requirement during treatment, the more the better. We like to recommend 3-4 liters per day. It's important to keep the urine output a constant pale yellow. The requirement is a direct result of the drug(s) action on your metabolism. It sucks it out of you! I know if you up the intake as suggested, you'll feel better. Carry a reuseable bottle with you and keep it filled. Sip on it all day long, it's a good habit to get into.

Welcome to the forum! I look forward to your progress 

Yup, water is very important!

Are you on any other meds, for other conditions, or herbal sups, etc?

When is the next time you get to go back and see your doc?

If you have a hint (yourself) that it may be better for you (and your symptoms) that it may have some beneficial effect (perhaps be better) to take your HCV meds (say) at supper or bedtime, rather than noon?, then you must do so with the advice of your doc, if he agrees that this may make any dif (and you might be the only one to "guess" at this), then he can instruct you in how to carefully adjust the time you take the dose, slowly adjusting (usually one hour later each day) until you reach the mutually agreed upon later time you have decided on. 

I really can't tell you whether the time you take your dose will make a dif. in how you are feeling. 

I know the water (big-time) should. So will taking exceptionally good care of yourself.

Instructions say you can take the sof/dac with or without food, so, if you don't have any reason against doing so, I would always opt to take my meds with food. And of course with lots of water prior, during and after!

You need to be trying to treat yourself very well right now. Eating and drinking the very best you can. Trying to deal with stress the best ways you can think of, resting as your body as it demands (even if you are having sleep disturbances), but still forcing yourself to move about out in the fresh air a little bit. 

You have to take care of yourself the best ways possible that you can think of and muster - it will help. C.

Fish and guru Thanks a lot for your comments I drink water at night but not enough during the day I will definitely start doing so the first couple days weren't bad at all I sleep a lot but not so much at night.yes and today just not as wel.l But got a lot of stress I,dealing with too. I will for sure start drinking more water during the day In ya,lls experience was their a better and worse time of day to take your meds .Im  taking mine at noon. Guys thanks a lot.    gator

Gator,

BCfish is quite right, about the importance of water. MAKE SURE you are drinking A LOT of water, probably you need to drink MORE than you are, even if you THINK you are drinking enough.

Believe us, please. The water WILL help and it IS necessary.

Sorry you are off to a "not feeling good" start. Not all, but quite a few people feel something, especially the first week or weeks, which is unfortunate when that happens, another person on the same drugs, can have a whole dif experience! and feel virtually nil (just to really add insult to the injury)! 

I was so jealous of a couple of my drug treatment counter-parts (we were all on the same drugs, but a totally dif regime than you tho), they felt virtually little to NOTHING, while I felt lots of stuff!!

I know a fellow (one only) who was on 24 weeks of sof/dac and he had troubles, but it eased toward the end, but he had a "rare and special" trouble that caused it tho, and his doc finally figured out he had been "accumulating" the drug in his system too well, due to this guys extremely high intake for certain fruits and foods that allowed his body to accumulate more of the drug than most people do, so, in his odd-man-out/isolated case, it gave him more opportunity for side effects.

I am not saying this is so in your case (accumulation), but read the sof/dac labels/food and drug interaction info to just assure yourself you are not taking anything that will not agree with the sof/dac. I am guessing you are having the standard unlucky feelings associated with just being on powerful drugs, the effects of all those viruses being killed off inside you, and maybe feeling it in a concentrated way (if you are not drinking enough water).

What kind of things are you feeling? 

I am betting with copious/ample water intake and a bit of time, it is going to lessen for you. C.

Hi Gator1959,

Sorry to hear your not feeling so good. I finished 24weeks of the same meds 2 months now. I didn't have any problems. I made sure I didn't get dehydrated. If you didn't know drink lots and lots of water. It should get better in a week or so from what I've read. Hope you feel better soon.  

Started savadi and daklinza 4 days ago last couple days not so hot I hate thinking its going to be like this for 12 wks don't get me wrong I,m grateful for the new med,s  just wanted to know if it got any better.