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Hep C Discussion Forum -> Hep C News -> Vertex announces 2 All-Oral Phase 2 studies with BMS of VX-135 in Combination with Daclatasvir
Post Info TOPIC: Vertex announces 2 All-Oral Phase 2 studies with BMS of VX-135 in Combination with Daclatasvir
Cinnamon Girl


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Vertex announces 2 All-Oral Phase 2 studies with BMS of VX-135 in Combination with Daclatasvir
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 Friday, April 5, 2013

Vertex Enters Agreement with Bristol-Myers Squibb for Phase 2 All-Oral Studies of VX-135 in Combination with Daclatasvir for the Treatment of Hepatitis C

 -Two Phase 2 studies to evaluate once-daily combination of Vertex's investigational nucleotide analogue VX-135 and BMS' investigational NS5A replication complex inhibitor daclatasvir

--Study in people with genotype 1 hepatitis C planned to begin in second quarter of 2013

--Study in people with genotypes 1, 2 and 3 hepatitis C, including people with cirrhosis, planned for second half of 2013-

 CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Vertex Pharmaceuticals Incorporated today announced it has entered into a non-exclusive agreement with Bristol-Myers Squibb Company to conduct Phase 2 studies of once-daily all-oral treatment regimens containing Vertex's nucleotide analogue hepatitis C virus (HCV) polymerase inhibitor VX-135 and Bristol-Myers Squibb's NS5A replication complex inhibitor daclatasvir for the treatment of hepatitis C. As part of the agreement, Vertex plans to conduct two Phase 2 studies of the combination, including an initial study in treatment-naïve people with genotype 1 HCV infection planned for the second quarter of 2013. Vertex plans to begin a subsequent study in treatment-naïve people infected with genotype 1, 2 or 3 HCV, including those with cirrhosis, in the second half of 2013, pending data from the initial study.

Full article...

http://hcvadvocate.blogspot.ca/2013/04/vertex-enters-agreement-with-bristol.html



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
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Hep C Discussion Forum -> Hep C News -> Vertex announces 2 All-Oral Phase 2 studies with BMS of VX-135 in Combination with Daclatasvir
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