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Post Info TOPIC: First normal ALT for 43 years


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RE: First normal ALT for 43 years
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CONGRAGULATIONS!



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great news for a good guy, gives me information that tests to improve after SRV and takes the worry out of results for now, congradulation

Bill emma and rave



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Geno type 1  rib and peg September 2012 , 5 weeks tripple and viral down to < 15 und april Aug 25 finished stay at peg 3 rib and eprex + blood transfussion finished treatment Aug 25 2013

KLG


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That is such great news! 36, wow!

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Geno 3a, stage 3, IL28 cc, diagnosed 94, interferon 1year, relapsed immediately, started RIBA/int on 2/1/13, 4 wk und. Female, age 55, EOT 7/18/13. 4 weeks UND, 12 weeks UND, 6 months UND!!!



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That's really great Malcolm. Now I can stop worrying about my levels!


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Geno 1A, since 1981. SOT 1/2013   TX stopped 11/2013 in week 45/48 due to Myositis & Interstitial Lung Disease. Completed 94% of Peg-Inter dbl TX, UND since week 4.  SVR 4/2014!  Still SVR after 4+ yrs!

"Day by day, step by step, breath by breath"



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Malcolm,

Congrats, those numbers look great. Treatment sucks but its amazing to see your numbers fall in line like that. Hope it keeps getting better every day

 



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John


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Hi Malcolm, That's an amazingly long journey,  I'm so glad that chapter in you life reached a successful conclusion.



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"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 



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How wonderful, Malcolm, and so encouraging for many of us here to see how your liver enzymes have normalised at last. You really deserve this, after 43 years of Hep C and enduring three bouts of very difficult treatment!

Thanks for sharing your good news, very pleased for you! 

 

 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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mallani,

this proves to all that persistance & determination pays off w/ this disease.

also it quite clearly is indicative of the regenerative ability of our liver to heal.

wow...congrats and have a banner of a celebration.

sandy,ucbgal



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wow 36! that was probably scifi score for you back one year ago ;) congrats! One day maybe even get low as 20!

btw, whats your FibroScan score?



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GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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Hi Tig,

Thanks mate. The AST:ALT ratio is said to be be a pretty accurate predictor of cirrhosis if >1.  In my case, there were only 2 occasions when this was >1 and you correctly spotted one.  I suspect my very high Fibroscan score was due to fatty liver, rather than very advanced fibrosis, as my albumin, platelets, INR and bilirubin have never been abnormal. It's a complex subject.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm

Tig


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Hi Malcolm,

Certainly not a bore! It's interesting to follow the progression of disease through treatment and I believe it's very helpful for some people to have these values to compare to their own, providing similar situations and treatment regimens. I do have a question regarding your ALT though. I know you're cirrhotic and I see only one instance (12/12) of the "lower than AST" value indicative of cirrhosis and that was after 11 months of triple tx. Are there any special circumstances responsible for that? Whatever the case, congratulations for your 43 year low (normal)!! You earned that and then some! Thanks...

Tig



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Hi all,

Sorry to be a bore, but my doc told me my liver enzymes would probably never be normal. The dental surgeon inserting the 3 titanium screws for my implants wanted some recent labs, so another blood test yesterday. The guy was worried I would bleed to death on him, as one of the screws will just go into the maxillary sinus, and he was remarkably ignorant about HepC.  Naturally I gave him a lecture, and told him to get up to date.

 

                      GGT     AST     ALT     Hb.     Platelets

Dec.2011         134      128      142     16.2      166k  ( pre-Tx)

Dec.2012         182      100       91       7.9       46k   ( after 10 months of Victrelis triple)

Dec.2013          46        38       44      15.9      159k  ( 10 months post-Tx)

Jan.2014           39       31        36      16.7      171k  (11 months post-Tx)

My enzymes were first noticed to be raised at my Army discharge medical in 1970. I was told to go easy on the booze, which was poor advice for some-one who just did 12 months service in the then South Vietnam.

My enzymes were again noticed to be abnormal in 1975, then again in 1982. That's when I had my first biopsy, which was normal.

I began keeping records in 1987, and the ALT has ranged from 80 to 350 since then. Naturally I'm a bit happy to join the normal ALT club, as it shows my liver is pretty calm these days. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm

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