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Post Info TOPIC: Congratulations Mallani


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CONGRAGULATIONS MALLANI!!



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The Virologist/Molecular Biologist from my Lab. gave me some interesting information, along with my Undetected VL result.

The Government has been making a fuss about paying for VL testing under our Medicare system. My Lab has just installed the new Roche Qualitative Test machine, which is accurate to a LLOD of 15 i.u./ml. This is the same sensitivity as the Quantitative test but is less than half the price ($400 vs $1,000). My tests are done for free, so I had both done. Evidently, once Undetected, followup VL testing will just be Qualitative to keep Medicare happy. I'm not sure whether this will happen in the USA.

Roche have also changed the structure of their 'Target'. This is still taken from the 5'UTR of the viral genome, and the 3 big players in VL testing, Roche, Labcorp and Abbott, closely guard the exact structure. Roche claims this refined 'Target' is even more accurate than before.

So don't be alarmed if the VL test result looks a bit different. Cheers.

 



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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Congrats on your SRV52, Malcolm, good reason to keep smiling!  smile



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Cheers Malcolm! thats about it, no more pesky hepatocytes munchers anywhere left hidden ;)

hows liver recovering? You taking any supplements or meds to help regeneration?

best



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GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!




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Congratulations!

Enjoy your life! and thank you very much for sharing your time, knowledge, and empathy.



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52 yo. Genotype 1a. 1.500.000 VL. Fibroscan : 8 . Probably I infected in 80s. I´ve never been treated. I've started Harvoni, 9/02/2015. 12 weeks. 



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You are an inspiration - well done.  Nxxxx

 



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Tig


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Hey Malcolm,

SVR +52, wow! That pretty much confirms it, eh? Congrats mate, that's excellent news for you and I'm certain there are plenty of smiles to go around in your family too. Now the next good news I'd like to hear from you, is the regression of your fibrosis score. That would be the "Cherry" on top! Good luck...

Tig

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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Congratulations Mallani!!! 1 yr hep c free!!! That is just fantastic!!! Thank you for all of your support, knowledge and inspiration for myself and for all members of this forum! I wish you continued good health, happiness and a hep c free life!!! It is definitely well deserved! And thanks again for all of continued support!

You are an inspiration to us all!  smile



-- Edited by kristi6 on Tuesday 18th of February 2014 05:16:02 AM

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57 y.o. 48 wks tx, peg/rib 2008. Relapsed @ EOT. Started peg/rib/vict 08/07/13. Geno type 1. VL Pre-tx 1.46m.@12wks Undetected!!! 24wks Undetected! F 3-4. 2nd time around. Hope to achieve SVR!!! EOT 7/7/14 Undetected 3 mon. Looks good for SVR!!!



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Hi again,

The VL test remains Undetected so I'll call that SVR 52 and get on with my golf handicap.

Thanks for all the kind thoughtful comments. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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Congratulations on the year, and Thanks for all the help and info. By the way, your looking great! And so is your wife, beautiful lady!



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John


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Congats Malcolm

Knowledge is power, and in your case your knowledge has been very powerful for all of us members of the forum. 

matt



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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 



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One day this forum won't be needed as biochemists perfect their knowledge and treatment for this disease! We are all in the historical shift of this disease and we are seeing first hand the miracles of science. Thanks for the medical knowledge, it is indeed helpful to know what is happening to us and to understand what it implies. When looking through the net, we are bombarded with information that at times is nothing short of frightening and mainly infactual or outdated. I no longer search the net for answers as most of them can be found on here. I will never have a perfect medical understanding of the disease, but facts seem to take away the fear factor and I concentrate on that rather than what may or may not happen. The future is brighter for everyone and it is indeed sad that not every person on this planet will be able to access these much needed meds in time, we can only hope they can battle through and wait. Saying that, congratulations on a full year and hanging around for others to help in their journey, and to Jill and other members that donate their time and efforts, cudos folks!



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Genotype: 3b

VL.ïż½over 15, 000 000

Failed TX 2014: Interferon/Riba.

Cured using Sof/Dak combination.

I can eat cake again! <3 



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Congratulations, Malcolm.

Your contribution to this forum is immense.

You have given a lot of information and insights to anxious people.

May God bless you!



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31 year old Indian

Starting viral load 2.3 million

Started treatment: 31/12/2013 with pegylated interferon and Ribavarin.

Fibroscan score : 5.3 kpa

GT : 3

EOT: 16th June 2014



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Congratulations Malcolm! And, thank you for sharing your medical knowledge with all here, that we may better grasp an understanding of the procedures, the lab test results, and the implications of the medical trends worldwide.    Best wishes to you, and since it seems that you're never far from a body of water, best of luck fishing as well. 



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"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 



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Malcolm,
We went thru tx at the same time!
You are my forum pal forever and always.
We went they some low periods but
We achieved SVR! Both 48 weekers.
Grateful for you and plan on having
Life time friendship thru forum.
This forum was a great help to me.
I CAN NOT imagine tx without it
Or without Malcolm and Cinnamon!

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JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!



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Hi SuziQ et al,

You guys are sharp! Yep, 12 months since EOT and to celebrate I had a blood test this morning. Two hours later, the Lab rang with the results- they are getting pretty efficient!  All normal, but the platelets are still a bit low. I get the VL this afternoon but I hope to continue my Undetected run- it's now 94 weeks since I had detectable virus.  I get to see my doc on Thursday, probably for the last time as he's now Dean of our biggest Medical School.  I'll be handed on to one of his younger colleagues.  Any questions members want asking?

I must say I survived the triple pretty well. The first 9 months were disappointing, with muscle and joint problems, but they have virtually gone. As I'll probably live longer than I expected, vanity has set in, so the dental issues are being addressed, so I can smile more!

I'm happy to help, as this Forum supported me through my lowest moments in treatment. I realise that not everyone has the same technical interest in our virus, so it's hard to know how much detail to go into. I've cancelled some of my on-line subscriptions as HepC treatment is approaching perfection. My only regret is that it will take a long time for some countries to access this. I am in awe of the Virologists and Biochemists who have unlocked most of our virus ( which still can't be cultured).  When you swallow one of their drugs, give thanks!  Cheers and thankyou.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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Congratulations Malcolm!!  You are awesome!! I second, third, fourth, etc what everyone else said. Thank you for your knowledge and insight - it is a big help to all the dragon slayers lurking amongst these pages!



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Born HepC + in 1983 ... diagnosed @ age 13 ... GT2 ... 12 wks of Sovaldi/Riba from 2/11/14 to 5/5/14  #ribazombie

1/30/14 - Starting VL 1,922,967 * 3/11/14 - UND @ 4 wks * 7/29/14 - SVR12 * 11/6/14 - SVR24 * May 2015 - SVR52 * MAY 2016 - STILL UND * FEB 2018 - STILL UND

 

HR


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Congrats Malcolm, you've been a great help to me through this forum and PM's. You provide top notch info and I can't thank you enough. I guess it's SVR 52 for you:)



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ION-3 Trial- Sofosbuvir/Ledipasvir 12 weeks.. UND 4 weeks, relapsed 12 week EOT. 

3-4 on Ischank scale

 

Retreat ION-3 Trial- Sofosbuvir /Ledipasvir 24 weeks

GT-1 (1-31-14) Week 1 VL 62 -Week 4,8,12,16,20 UND EOT 7-18-14



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Well said, SusiQ, and everyone else too!  Congratulations, Malcolm, how wonderful to think it`s a year now since you achieved your very well deserved SRV!!!  biggrin

Thanks so much for all you do here, you have single handedly raised the standard of knowledge on this forum by quite a considerable degree!  We all appreciate you sharing your knowledge, understanding, and experience with us all here, and I know I`ve personally learned such a lot from you and continue to do so.

Wishing you nothing but the best in your Hep C free life...we can see the joy in your happy smiling face!  ~ Jill



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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CONGRAGULATIONS!



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Congratulations on your first year virus free! Providing your knowledgeable insight, wisdom and kind consideration to members of this forum has clearly been invaluable to all of us. Your posts help bolster our confidence that we can beat this disease and have a meaningful and active life to follow. Enjoy!



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Geno 1b, compensated cirrhotic, 54 yo, prior null responder. Pre tx VL approx 595,000, tx with Sovaldi/Olysio (no Riba) started 1/8/14. VL 40 @ 2 weeks, UND @ 4 weeks. Still UND @ EOT + 1 year.

Gator Man SVR12, Dragon 0, Final Score.



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Way to go Malcolm!  Congratulations!



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Me: 62 yr. old female, GT 1b, fibroscan 4.5; VL 650,975 as of 2/4/14;started Harvoni 3/6/15; SVR


Hubby: 59 yrs.; GT1b; fibroscan 25-cirrhotic; S/O for 12 weeks started tx 3/20/14; SVR56; fibroscan done 7-7-15 = 8.5



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Congratulations one your one year up. Thanks for all your invaluable information.

cheers mate.



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GT3a Age 61. Clinical trial sovaldi/riba 24 weeks. finished trial 17th April 2015 undetected. EOT+4 weeks undetected.24th July 2015 "SVR"

24 week SVR!!

Tig


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I'll second that! Malcolm, your help and assistance meant more to me than you know. Your positive approach and the distance you're always willing to go to discover the truth, kept my hopes high and my mind on the goal. Congratulations on reaching this milestone in your treatment and life. Thank you!

Tig

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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Congratulations on your one year post treatment.

You are such a help to us all--and caring in your posts--sharing information many of us have no access to.

Thanks for all you do !!!!

Suziq

I do hope I have the right date  Feb 15, 2013  ???



-- Edited by suziq on Sunday 16th of February 2014 03:07:40 PM

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Geno 1A  Age 82 Treatment naive Cirrhotic Told I had liver disease in 1966. Diagnosed as Hep C 1999.Started Merck clinical trial with Riba on 9/9/2013 Week 1 and 2 <25  Weeks 4, 8, 12,16,18 UND.  EOT Jan 14,2014  EOT +12 UND   JULY 1 2014 EOT+24= SVR

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