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Hep C Discussion Forum -> Hep C News -> Clinical trials started for TT-034 an injectable hcv tx.
Post Info TOPIC: Clinical trials started for TT-034 an injectable hcv tx.
maddie


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Clinical trials started for TT-034 an injectable hcv tx.
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Pretty interesting article about new clinical trial involving one injection of TT-034. 

SYDNEY, May 29, 2014 /PRNewswire/ -- RNAi-based therapeutics company, Benitec Biopharma Limited (ASX: BLT) announced that it has dosed the first patient in its 'first in man', Phase I/IIa clinical trial for TT-034, a ddRNAi-based therapeutic, designed to treat and potentially cure hepatitis C (HCV) with a single injection.

The Phase I/IIa clinical trial is an open label, dose escalation study in a total of 14 patients chronically infected with HCV genotype 1. Initial patient cohorts will be treated with a sub-therapeutic dose of TT-034 to ensure that there are no unexpected safety concerns, before proceeding to higher, potentially therapeutic doses.

http://online.wsj.com/article/PR-CO-20140529-906886.html



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Dx. 2005-liver bx.: stg 2/gr 1. at that time  - GT 1a multiple transfusions in 1981.  Started Sovaldi and Olysio 1/16/14  (No prior treatments) Q80K present.  UND week 4,8 and at EOT.   UND at wk 4EOT, Und at wk 8EOT  SVR 12!!!..SVR 24 :-)
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Hep C Discussion Forum -> Hep C News -> Clinical trials started for TT-034 an injectable hcv tx.
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