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Post Info TOPIC: 8 weeks eot still und


Guru

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8 weeks eot still und
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It takes about 6 months for the riba to completely leave your body, Nicole.  I just had a look at the full prescribing information for Sovaldi and this is the advice given...

"When SOVALDI is used in combination with ribavirin or peginterferon alfa/ribavirin, women of childbearing potential and their male partners must use two forms of effective contraception during treatment and for at least 6 months after treatment has concluded."

Scroll down to section 5...

http://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/sovaldi/sovaldi_pi.pdf

So after the 6 month post tx point has past then you`ll be free to start planning your baby. 

Good luck, happy times ahead!!  smile

 



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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When is it completely out of your system? I'd like to have a baby sometime

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Genotype 1a

1/18/13 -  VL 1.5mil triple therapy with boceprevir

2/3/14 - relapsed. 1.7ml

 

6/28/14 - started solvadi interferon and ribavirin for 12 weeks

7/28/14 - week 4 undetected dosage reduction of rib and peg

 

11/2/14 und 4 weeks post eot

 

g

 



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I think we'll have two SVRs in the very near future. Good news for both, Nicole and Marcy!



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Geno 1b, compensated cirrhotic, 54 yo, prior null responder. Pre tx VL approx 595,000, tx with Sovaldi/Olysio (no Riba) started 1/8/14. VL 40 @ 2 weeks, UND @ 4 weeks. Still UND @ EOT + 1 year.

Gator Man SVR12, Dragon 0, Final Score.



Guru

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Way to go! Marcy UND on your way to SVR

matt



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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 



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All sounding positive for SVR!   I too am undetected 10 weeks after treatment and am feeling very good.  I never really realized how bad I felt all the time for SO MANY years until now!

 

Great news for you!!!



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Marcy

Long-term HCV, GT1a, IL28B C/T, T/G;  VL 2 mil.  Merck C-Edge Clinical trial  EOT 10/01/14. +24= UND



Guru

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Great news on the UND Nicole Wish you a speedy SVR and Full hair



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Bills

Harvoni started 12-12-14 for 24 wks PrevTX Geno 1 stage 3 cirrhosis - non resp Int/ ribv. Started Trial  in Aug 2011 -July 2012 into Incivek relapsed  Feb 2013 Had 72 weeks on interferon & Riba.



Guru

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I feel for you with the hair loss, Nicole, and I remember mine continued to fall out for few weeks post tx.  I agree with Malcolm that it should ease off and start growing back within the next few weeks as the riba clears from your system.  I know how annoying it is having hair falling out everywhere but the main thing is you`ve got through your tx and you`re heading towards SVR!!



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



Guru

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Hi Nicole,

Congrats on the 8w-post Undetected. You're almost home.

Hair loss continues for a while as Riba is slow to leave the system. It'll gradually improve and by week 12 I'm sure it will be growing back, better than ever. Cheers.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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When will my hair stop falling out? I almost wish it'd all fall out at once I'm disgusted by the hair all over everything.

__________________

Genotype 1a

1/18/13 -  VL 1.5mil triple therapy with boceprevir

2/3/14 - relapsed. 1.7ml

 

6/28/14 - started solvadi interferon and ribavirin for 12 weeks

7/28/14 - week 4 undetected dosage reduction of rib and peg

 

11/2/14 und 4 weeks post eot

 

g

 



Guru

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Hi Nicole, good to hear from you, and congrats on still being UND!

I think at this stage, 8 weeks post tx, your chances of SVR are looking very promising indeed, so go with your feelings of optimism and keep looking forward.  I know this time of waiting must be hard for you after your bad experience last time with the victrelis triple but this time you had Sovaldi in the mix.

Really pleased you`re feeling so much better already...onwards to SVR!!  biggrin



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



Senior Member

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Being UND for so long you had a good chance of being SVR. Feeling better is also a good sign. Keep thinking positive. I know it was difficult waiting for the news and I tried to think about it as little as possible until a couple of weeks before hearing that I was SVR. Live and try not to dwell on your status, but do eat healthy and get plenty of exercise. Hope to hear good news from you soon.

gigi



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genotype 2 completed sovaldi and ribavirin on 6/4/14. SVR on 12/3/14



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We can never know the future but there is every reason to believe you are going to beat this bug once and for all. I'm really glad to hear the SEs & symptoms clear quickly.
I have this theory about how minds are affected when bodies are fighting off a major infection. I think it stimulates the flight/fight response or at least makes it more sensitive. HCV can be subtle, but increased confidence and a sense of well being when cured fits my theory.

Full steam ahead!



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I can't explain it really.  I just feel different.  Like clear. Not tired or foggy all the time.  I felt confident at the 4 week mark I was und and at the 8 week mark.  I hope it stays und.     When I relapse w victrelis. I felt like I wasn't surprised.  Like I could tell I still didn't feel good.   



__________________

Genotype 1a

1/18/13 -  VL 1.5mil triple therapy with boceprevir

2/3/14 - relapsed. 1.7ml

 

6/28/14 - started solvadi interferon and ribavirin for 12 weeks

7/28/14 - week 4 undetected dosage reduction of rib and peg

 

11/2/14 und 4 weeks post eot

 

g

 

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