Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Hep C Discussion Forum -> On Treatment -> Ever wondered how can liver enzymes stay so low, while interferon & RIBA toxins go in??
Post Info TOPIC: Ever wondered how can liver enzymes stay so low, while interferon & RIBA toxins go in??
mallani


Guru

Status: Offline
Posts: 3398
Date:
RE: Ever wondered how can liver enzymes stay so low, while interferon & RIBA toxins go in??
Permalink  
 

Hi Margo, Retired Radiologist, specialising in upper abdomen imaging. Since 1990, attended every meeting I could about HCV.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Margo


Senior Member

Status: Offline
Posts: 459
Date:
Permalink  
 

Mallani you are a pro, medical background?

__________________

Geno 1b, relapsed in 2009 a week before my treatment was to be over. Started triple therapy on April 28th, 2012. UND at week 4,8,12,24,3 months post tx.
Biggyb


Guru

Status: Offline
Posts: 820
Date:
Permalink  
 

My enzymes were always about triple the normal range. 4 week blood test since i started treatment the are in normal range..



__________________

58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~
mallani


Guru

Status: Offline
Posts: 3398
Date:
Permalink  
 

The normal range for AST and ALT is 5-45 (depending on lab.) . These enzymes are released from hepatocytes as a result of liver cell damage or death. Chronic HCV often causes mild elevation of enzymes. However this is very variable, and even cirrhotics can have normal enzymes, so this is not a test of liver function. More reliable tests are albumin, prothrombin time, bilirubin and alkaline phosphatase. Mild fatty liver and many drugs can cause elevated enzymes. So, liver function may be entirely normal even with elevated enzymes.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Judy S


Senior Member

Status: Offline
Posts: 360
Date:
Permalink  
 

Margo, I've wondered the same!!!  At Week 2 of tx, my liver enzymes fell to within normal range and remained. 

AST has been 36, 23, 22, 27, 21, 19.

ALT has been 50, 44, 17, 16, 16, 11, 28, 23, 32, 16.



__________________

Geno 1a; VL 4.7 million in Feb 2012. Started PegIntron & Ribavirin 3-9-12. Added Victrelis 4-6-12. UND since Week 8. Stopped tx Wk 23. UND 4 Wks post-tx. Relapsed 12-weeks-post.

52 y/o F, started Epclusa 11-10-19, F0/F1.  EOT 2-1-2020. UND. All liver function tests normal.
Margo


Senior Member

Status: Offline
Posts: 459
Date:
Permalink  
 

My liver enzymes are 18! How can liver detox So much crap?

__________________

Geno 1b, relapsed in 2009 a week before my treatment was to be over. Started triple therapy on April 28th, 2012. UND at week 4,8,12,24,3 months post tx.
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.
Hep C Discussion Forum -> On Treatment -> Ever wondered how can liver enzymes stay so low, while interferon & RIBA toxins go in??
Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.