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Hep C Discussion Forum -> Hep C News -> Gilead Wash. DC study, 100% cure rate 12 wk. & 6 wk
Post Info TOPIC: Gilead Wash. DC study, 100% cure rate 12 wk. & 6 wk
Gracie


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RE: Gilead Wash. DC study, 100% cure rate 12 wk. & 6 wk
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This would be the bomb to participate in.... Can you believe it? 6 weeks, 100% cure!

Sovaldi, ledipasvir, GS-9451 6 weeks 100% cure rate



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  1. Gracie

1A. Previously treated non responder Rebetron in 2000 And Incevik in 2014 with a breakthrough at week 12. Fibroscan 15.5. VL 6,000,000. Finished 24 weeks harvoni on Dec. 19, 2015. SVR. Latest Fibroscan 8.8.
Fireman Rob


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I love you all for such quality information- which is helping me stay positive!



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Age 33, Male. GT-1 for ten years. Diagnosed in March, 2014.

Treated with Sovaldi/Olysio: SVR 24 on February 16, 2015!
Greg


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Cheers from the sidelines, things are looking up. 

 



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The mind is like a parachute it works best when it is open. "The Dalai Lama" My blog: http://greghcv.wordpress.com/
Genotype 1a, started tx 1st Feb 2011, for 48 wks. Week 24 PCR 26/07/11 Non-Responder
New TX start date 12th Sept 2016 Harvoni x24 weeks.  VL 7.4 Mil. Week 4 "Undetected"
Jener


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I just wish I had known about this study, since I live in Washington DC.

no

Instead, I'm doing Sovaldi+Riba for 24 weeks. I shouldn't be complaining, and I'm not really. Already UND after the third week.

But it would've been nice to take meds for only 6 weeks and be done with it.



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Geno 1b, diagnosed in 2005. Started Sovaldi+Ribavirin on 3/5/2014, undetected on 3/28/2014.

Relapsed after EOT on October/2014.

Started Harvoni on 3/2/2015 for 24 weeks.
Rybronco


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What a thrill to read about the new drug studies and combinations that are producing staggering cure rates. 

First in the U.S. then worldwide we will no longer have to encourage those with heavy sides to persevere.  A Motrin for an annoying headache from time to time and you are cured in 6 to 12weeks!

Beautiful and a blessing for all of us.

 

Rockon!



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49 yo. G1a prior tx 2005 with peginf and RIBA 12 weeks dc due to side effects. vl 7.8mm Current tx Sovaldi/Olysio 12 weeks started 2-21-2014,  UND at 4 weeks, EOT+12 SVR
Cinnamon Girl


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Yes, Maddie, it certainly is like a miracle compared to the limited treatment options people have had up until recent times.  Whoever would have believed that medical science in the field of Hep C would have made such huge strides forward! 

All the best of luck to you with your results, not much longer for you now, and it certainly looks very promising.  You`ve responded well all along and we look forward to hearing more good results!

Thanks for the news updates and all your supportive posts on the forum.



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
maddie


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Thanks, Jill.  It is just so wonderful, isn't it?  Finally, a treatment that is safe, minimal sides and best of all, highly effective.  What a miracle we are all witnessing.  I hope that the combo I am just about to finish, Sovaldi/Olysio, will be my miracle...as well as all those on it.  Thank you for being here for all of us. 

Tig, Gracie, I think that as more drugs are approved, the price will come down.  It was good to see that this particular study conducted in Washington DC included mostly low income patients.  And now they are Hep c free!

 

 



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Dx. 2005-liver bx.: stg 2/gr 1. at that time  - GT 1a multiple transfusions in 1981.  Started Sovaldi and Olysio 1/16/14  (No prior treatments) Q80K present.  UND week 4,8 and at EOT.   UND at wk 4EOT, Und at wk 8EOT  SVR 12!!!..SVR 24 :-)
Cinnamon Girl


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Thanks for posting this, Maddie, these are some impressive results!  The future is looking very bright for Hep C treatment options and this combo is leading the way!  And I agree absolutely with what Tig and Gracie said, let`s just hope the price will be set within reasonable limits so that as many people as possible can benefit from this amazing advance.  

I`ll do a separate post for an overview of the April HCV Advocate Newsletter. 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
Gracie


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If they would just realize they won't need to charge that much. With hep c screening becoming standard, and with shorter easy to handle treatments, most people will treat. I'm sure the old SOCs kept lots from trying. They will make tons and tons of money in numbers alone. This is a cure! So very hard to believe this is so close! Come on drug companies.... 



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  1. Gracie

1A. Previously treated non responder Rebetron in 2000 And Incevik in 2014 with a breakthrough at week 12. Fibroscan 15.5. VL 6,000,000. Finished 24 weeks harvoni on Dec. 19, 2015. SVR. Latest Fibroscan 8.8.
Tig


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Sovaldi and Ledispavir are going to be the go to combo! I'm glad that Gilead is on the carpet now for price gouging on the singular drug Sovaldi. God only knows what they would (will) try to charge for this single pill combo when approved by the FDA this year or early 2015. Let's hope wiser, more compassionate minds prevail when they structure the initial price to consumers...

Tig



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Gracie


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Oh my gosh.... This is incredible! This has made my day. Thanks Maddie. So hard to believe a 100% cure is so close..... And 6 WEEKS! Wowza!


Sovaldi, ledipasvir 12 weeks 100% cure rates

Sovaldi,  ledipasvir, GS-9669 6 weeks
95% cure rate

Sovaldi, ledipasvir, GS-9451 6 weeks100% cure rate


__________________
  1. Gracie

1A. Previously treated non responder Rebetron in 2000 And Incevik in 2014 with a breakthrough at week 12. Fibroscan 15.5. VL 6,000,000. Finished 24 weeks harvoni on Dec. 19, 2015. SVR. Latest Fibroscan 8.8.
maddie


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In the April HCV Advocate, info presented at the 2014 CROI is reported.  Page 7 shows results of the study.  Link to the newsletter below.  (Need to download printable version to see in newsletter form.)

http://www.hcvadvocate.org/news/newsLetter/2014/advocate0414.html#1



-- Edited by maddie on Sunday 6th of April 2014 02:12:33 AM

__________________

Dx. 2005-liver bx.: stg 2/gr 1. at that time  - GT 1a multiple transfusions in 1981.  Started Sovaldi and Olysio 1/16/14  (No prior treatments) Q80K present.  UND week 4,8 and at EOT.   UND at wk 4EOT, Und at wk 8EOT  SVR 12!!!..SVR 24 :-)
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