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Post Info TOPIC: Sofosbuvir + ribavirin is safe and effective for HCV recurrence after liver transplantation


Guru

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Date:
Sofosbuvir + ribavirin is safe and effective for HCV recurrence after liver transplantation
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"An interferon-free combination of sofosbuvir (Sovaldi) plus ribavirin taken for up to 24 weeks led to sustained virological response in 70% of liver transplant recipients with hepatitis C virus (HCV) recurrence, according to a poster presented at the 49th annual meeting of the European Association for the Study of the Liver (EASL) held recently in London."

"Hepatitis C virus almost always re-infects the new liver after a transplant.   This can lead to rapid fibrosis progression with an increased risk of graft loss and life-threatening complications.  Interferon - the former standard of care for hepatitis C - is often poorly tolerated and not very effective for people with advanced liver disease.  Sofosbuvir is a promising option because it is well tolerated and does not interact with immunosuppressant drugs used to prevent organ rejection."

Full article...

http://www.aidsmap.com/Sofosbuvir-ribavirin-is-safe-and-effective-for-HCV-recurrence-after-liver-transplantation/page/2851593/

 



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 

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