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Post Info TOPIC: My Lab Tests Geno 1a
Brian1412


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RE: My Lab Tests Geno 1a
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Thank you 



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Brian1412


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Dr is scheduling Fibro  immediately .. 

 

  I think I don't want to mess with interferon at all



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LC


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If for some reason you can't get Harvoni, there are other combo's.  wink  In my 1a treatment naïve case, the AbbVie combo actually has the best clinical efficacy rate.  I don't care whether I am swallowing 9 pills a day or one, just so I don't have to repeat treatment, I will be happy.  I would have preferred to forgo the Ribavirin, but so far (2 weeks) it hasn't caused me any issues.  Merck's number aren't too bad either.  It's all preferable to Interferon shots to me.  smile

In case you haven't seen this yet - http://www.realendpoints.com/wp-content/uploads/2014/10/Harvoni-Press-Release-Slides.pdf

 

 

 

 



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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
Brian1412


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Thank you..   I will be pushing hard for the fibroscan on the next appointment  on the 7th. I did have a very extensive ultra sound done by  someone who knew what is going on and had done all my imaging since I had Tc 17 years ago. He knew why I was there and he loves my body because he can see very well and my pictures are in his books.   Needless to say  is that fibroscan is my next priority .

I beat a 100 % Chorio Carcinoma tc death sentence ,and with help and new meds ,hopefully this also .I have read up on the meds, and I guess if I need something, now is the time.

So here I go again ..  I appreciate all of you for being here ,and although I have confidence with this Dr, it is the other parts of the system I learned to watch like a hawk . My grant to cover everything is golden, and I understand  this isn't going to be easy, but I am ready .  I am sure I will have many other questions ,and I can use all the help in keeping everything focused.

 

Thank you all for being here.  R



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mallani


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Hi Rob,

The RT stands for Real Time, as just refers to the type of assay.

You Viral Load is 23.5 Million, which is high.

Geno 1a may be slightly harder to treat than Geno 1b, but with Sofosbuvir, there appears to be little difference. Certainly if a Protease Inhibitor is used, the 1b's do a bit better.

You need to get your liver assessed, by Fibroscan or biopsy. Then, if you have little damage, you can afford to wait until you can access Harvoni. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
LC


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Not with all the good new drugs coming out gunning for 1. Now I think genotype 3 may be more challenging.



-- Edited by LC on Thursday 23rd of October 2014 06:22:32 AM

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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
Brian1412


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OK,  I have the lab report

HCV log 10- 7,37  Hep C Geno   1 a with I think it is RT? after the geno type    so 1 a rt.. I have a whole page of results for the blood test, so I don't know what else to include.  Let me know and I will post everything. I don't have a scanner

I guess I got the jack pot.  1a is the most difficult to treat?



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