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Post Info TOPIC: ABBVIE Topaz II
Cinnamon Girl


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RE: ABBVIE Topaz II
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Hi Christine,

Good to hear you excellent news, congrats on your continuing undetected results and your SVR24!  I would most definitely agree that you are cured!!

I`m really pleased you`re getting your energy back now, it`s a gradual process and recovery does take time. 

Thanks for dropping by with your update, nice to hear from you!  smile

 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
Tig


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Congratulations Christine! Sounds like a solid SVR to me too. Time to enjoy your new Hep free life, woot!!! Good luck smile



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Matt Chris


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Hey Christine

Super congrats on your SVR, life is good for you. I am happy that all things have worked out.

matt

  


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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 
RAGDOLL


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Update on my clnical trial results  (SVR24)  6 months post treatment 7-7-15  Still Undedected.   Pretty amazing!  They say I am cured.   ALT still 43 but AST has gone up from 37 to 53  which is a little high.  They say it might be from my Arthritis medicine, Arthrotec, which I resumed taking since last blood draw in April.    It was suggested to stop it again and allow my liver to continue to heal.  Also my cholesteral is still a little high, 225.  Starting to get my energy back and my husband says my eyes look really clear.  So grateful for this trial.  



__________________

F 63,  1b  1974, no cirrhosis, fibro scan 5.8 F0-F1,fibro test .37 ,V/L 702987, ALT 90, AST 75.  ABBVIE Topaz II on 10-30-14 Viekira Pak no RIBA , EOT 1-22-15 SVR, ALT 37, AST 29, 4-15-15 SVR12 - fibro test .22,  1-21-16 SVR 52 ,  1-21-17 SVR 104! 1-21-18 SVR 3 years ,2020 5 years, 2022 7 years!
RudiRoo


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Add another congratulations Rag Doll! I got my happy news today and I am with you on that wonderful "blessed feeling"! 

Enjoy your happy!

~ Rudi



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Hep C since 1982, GT IL28b CC, tx naive, VL 2.5M, normal liver panel, Hepascore F-0, A-1. Sjogren's, Hashimoto's, Raynaud's, etc. SOT S/O 12 wk tx on 10.28.14. EOT 1.19.15. HEP C FREE AT LAST! 4.29.15
Cinnamon Girl


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Good to hear from you again, Ragdoll, and even better to hear your fantastic news!! 

Very pleased for you that your Abbvie trial has been so successful, thanks for sharing your results with us.

Congrats on SVR!!  biggrin

 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
Tig


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Hi Ragdoll,

Congratulations on finishing tx and your SVR!! Fantastic results and another success story! You made my day! This is not only a good morale booster for GT3's, but everyone else as well. WOOT!!



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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RAGDOLL


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Got my call Friday that my 12 week post treatment blood test still shows undedected.  I feel very blessed that this all worked out.   Keep praying for the type 3's. 



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F 63,  1b  1974, no cirrhosis, fibro scan 5.8 F0-F1,fibro test .37 ,V/L 702987, ALT 90, AST 75.  ABBVIE Topaz II on 10-30-14 Viekira Pak no RIBA , EOT 1-22-15 SVR, ALT 37, AST 29, 4-15-15 SVR12 - fibro test .22,  1-21-16 SVR 52 ,  1-21-17 SVR 104! 1-21-18 SVR 3 years ,2020 5 years, 2022 7 years!
Cinnamon Girl


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Hi Robert, that`s great news! 

So pleased for you and your wife, please send all our best wishes to Ragdoll and thanks for keeping us updated.

It`s looking very promising, onwards to SVR12!! 

 

 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
lilbit


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Awesome news on Ragdoll. Abvie is kicking dragon butt on a regular basis. Sorry couldn't resist.


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64 yo Diagnosed in 1991 with Hep C, Genotype 1a, VL close to 16,000,000, Tx Abbvie Topaz II 9/5/14, Wk 2 and 4 und. End of treatment 11/27/14 undetected.  EOT+4 und  EOT+12 und.  EOT+24 und CURED, EOT +52 now I feel really cured.
Tig


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Hi Robert,

That's excellent news! You've got this nailed Brother. SVR4 is a milestone! Good luck and keep us informed!

Tig



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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robertsamx


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Report Card on My Ragdoll.   4 weeks post treatment.   UND    Now just sitting back waiting for the  12 week post test.  RC



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 M-64) 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
Cinnamon Girl


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Great to hear your wife is experiencing no sx, Robert, that`s amazing!  You must both be so relieved it`s going so well.

Good going, Ragdoll, we`ll be looking out for your next update.  smile

 

 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
Tig


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Outstanding Robert!!! That's the kind of update we love to hear. We'll keep her in our thoughts and prayers! Keep us informed and tell her good luck from us all!

Tig



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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robertsamx


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Hi all, my wife is not having any s/x at all !!   She  says its just like taking vitamins. She has been pretty sensitive to meds over the years and  I was concerned she would have some kind of s/x but none have shown up. Going into week 6 of trial on truesday, so far so good!  RC



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 M-64) 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
lilbit


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Way to go Ragdoll. The weeks will fly and you will get this done. Great results so far.


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64 yo Diagnosed in 1991 with Hep C, Genotype 1a, VL close to 16,000,000, Tx Abbvie Topaz II 9/5/14, Wk 2 and 4 und. End of treatment 11/27/14 undetected.  EOT+4 und  EOT+12 und.  EOT+24 und CURED, EOT +52 now I feel really cured.
Cinnamon Girl


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Great result...congrats to Ragdoll!!  Thanks for letting us know, RC, and please let your wife know how pleased we are to hear about her progress!!  biggrin 

How is she feeling now, any sx?

Onwards and upwards!! 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
robertsamx


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Thanks Tig   were pretty happy around  here with this news.  She is 5 weeks into treatment now, and we got the good news yesterday..  At 12 days her V/L went from 800k to  just  30

 and at 4 weeks   UND!!         RC



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 M-64) 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
Tig


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Outstanding news RC!! Love those three letters UND, WOOT!

Tig



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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robertsamx


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update on ragdoll... She has 4 week blood draw results and is UND.   RC



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 M-64) 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
LC


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Aerosmith has a song called Ragdoll too.

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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
Isiscat2011


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Hey Ragdoll:

I just finished watching the movie "Jersey Boys."   The Four Seasons recorded a song for you that I hadn't heard in a long time.  Great song:

 

https://www.youtube.com/watch?v=kYBZqfOZiS4



-- Edited by Isiscat2011 on Tuesday 11th of November 2014 06:30:09 AM

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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
Cinnamon Girl


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Hi and welcome from me too, Ragdoll!  Thanks for introducing yourself...good to have you with us!! 

Sounds like you`re doing great so far, you must be so pleased your husband and medical team persuaded you! 

Looking forward to following your progress, best of luck!  smile

Btw..We do have a section called `Clinical Trial Participants` and you`re welcome to post your updates there. 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
LC


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Not shady, a very brave mousekitteer! It's an honor for the cat.

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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
Isiscat2011


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robertsamx wrote:

would your kitty like a ride in my 50 stude starlite coup??

OK, enough with the dirty talk you two.    smile   Oh my, I don't believe we have had a married couple posting at the same time.  It could get mushy.

 

LC:  The humiliation poor Isis must endure at the hands of your shady Mouse.  



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
robertsamx


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would your kitty like a ride in my 50 stude starlite coup??



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 M-64) 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
robertsamx


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Welcome, Like that ragdoll cat of yours.  Looks like a hand full.    I'M so glad you went with the trial, lots of folks have gone UND in the first two weeks on this forum.I"m keeping a very close eye on you , robertsamx sees all things (because I like cats too!)  Your doing so well  absent of S/X.   You made the right decision to go with this.  I told you so.   Thank you so much for going for it!!     RC



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 M-64) 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
lilbit


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Welcome Ragdoll. Excited to see more Topaz II folks. When I first came here I was the only one. There was one other that hadn't been on for a little bit and should be finished by now. Then LC came on and now you. I finish week 9 tomorrow and only have three left. If you aren't taking the Riba you should absolutely sail through this. Even on Riba it isn't bad at all. If I can help in any way, please let me know.

__________________

64 yo Diagnosed in 1991 with Hep C, Genotype 1a, VL close to 16,000,000, Tx Abbvie Topaz II 9/5/14, Wk 2 and 4 und. End of treatment 11/27/14 undetected.  EOT+4 und  EOT+12 und.  EOT+24 und CURED, EOT +52 now I feel really cured.
LC


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Hi Ragdoll!  Glad to see more Topaz II members.  I haven't really seen any side effects either, other than being a bit more tired the first few days.  I think my body was battling the virus hot and heavy about then.  Good stuff isn't it? smile

Isiscat2011 wrote:

  We need more cats in the forum.  

 Especially those who are broke to ride.  It's so hard to get good help these days, most cats just wear out so quickly. no



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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
RAGDOLL


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Yes, Ragdoll is a breed of cat!



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F 63,  1b  1974, no cirrhosis, fibro scan 5.8 F0-F1,fibro test .37 ,V/L 702987, ALT 90, AST 75.  ABBVIE Topaz II on 10-30-14 Viekira Pak no RIBA , EOT 1-22-15 SVR, ALT 37, AST 29, 4-15-15 SVR12 - fibro test .22,  1-21-16 SVR 52 ,  1-21-17 SVR 104! 1-21-18 SVR 3 years ,2020 5 years, 2022 7 years!
Matt Chris


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Hey Chris 

Welcome to the forum, its nice to have another member that is on the Topaz II trial. I have been on the meds that you are on and you hopefully fly through the time with no problems as most have done. If you have questions or concerns just ask and the forum members and they will try to respond.

matt 



__________________

"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 
Isiscat2011


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Welcome RAGDOLL:

Excellent!  There are others here on the Abbvie combo and all are doing well.  We need more cats in the forum.  Is that a ragdoll breed of cat, btw? 



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
RAGDOLL


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Hi, I have just completed 7 days of treatment today and am pleasantly surprised that I have had absolutely no side effects.   I just feel like I am taking a few more vitamins. It is truly amazing.  I thank God for this opportunity to be in this trial.   I was very hesitant to start this as when I got the call I was just 4 weeks post hip replacement surgery.  I didn't think I could handle the treatment after watching what my husband ( Robertsamx) had gone thru earlier this year with his treatment with Gilead which turned out not successful.  Also, I am very sensitive to drugs and had bad reaction to a Tetanus shot several years ago.   But the clinic and my doctors along with my husband encouraged me that this was the best thing for me to do and not to worry.  I am so glad I took their advise.    I hope the next 11 weeks are as easy as this first week.  I go for my 2 week check up next week.  We shall see how this treatment is working.  



__________________

F 63,  1b  1974, no cirrhosis, fibro scan 5.8 F0-F1,fibro test .37 ,V/L 702987, ALT 90, AST 75.  ABBVIE Topaz II on 10-30-14 Viekira Pak no RIBA , EOT 1-22-15 SVR, ALT 37, AST 29, 4-15-15 SVR12 - fibro test .22,  1-21-16 SVR 52 ,  1-21-17 SVR 104! 1-21-18 SVR 3 years ,2020 5 years, 2022 7 years!
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