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Post Info TOPIC: Gilead Sciences Gets Ambushed By The Patent Troll, AbbVie $
LC


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RE: Gilead Sciences Gets Ambushed By The Patent Troll, AbbVie $
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Isiscat2011 wrote:

Speaking of costs, an 8 week duration of Harvoni only costs 63K  (did I just say only?).  That may be in the same ballpark as 12 weeks of Abbvie.  So, the 8 weekers may actually stand the best chance of getting Harvoni.   In the longer term Gilead's new Harvoni + 1 will only be 6 weeks duration and cost predictions are ~the same cost of 8 weeks of Harvoni.  

Could be the longer duration patients end up having the hardest time getting the Harvoni, once Abbive is approved, at least in the short term.  That kinda sucks because the side effects for Abbvie + Riba over a 24 week course could get pretty rough.  Just speculating.  


Maybe, but as sneaky as AbbVie has shown themselves to be, with the patents and the tax situation, I doubt they are going to let Gilead steal a march on them with something so simple.  Even though they can't sale Harvoni themselves, they want to try and make Gilead pay them royalties on it!  biggrin  I must hand it to AbbVie's patent lawyers.  I do wish I had some extra money to play the market.



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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 



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LC wrote:

Maybe AbbVie will sale it too, eventually. No wonder they "weren't interested in getting into a price war". Haha on Gilead, it couldn't happen to a more deserving company.


Speaking of costs, an 8 week duration of Harvoni only costs 63K  (did I just say only?).  That may be in the same ballpark as 12 weeks of Abbvie.  So, the 8 weekers may actually stand the best chance of getting Harvoni.   In the longer term Gilead's new Harvoni + 1 will only be 6 weeks duration and cost predictions are ~the same cost of 8 weeks of Harvoni.  

Could be the longer duration patients end up having the hardest time getting the Harvoni, once Abbive is approved, at least in the short term.  That kinda sucks because the side effects for Abbvie + Riba over a 24 week course could get pretty rough.  Just speculating.  



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.

LC


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Maybe AbbVie will sale it too, eventually. No wonder they "weren't interested in getting into a price war". Haha on Gilead, it couldn't happen to a more deserving company.

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Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 



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Thanks Isiscat.  That is encouraging! Unfortunately pricing is exorbitant but I am hoping for insurance coverage.



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HCV Gen 1a diagnosed 2001; Labs 11/13/14: VL 1.2 million IU/mL, ast 88, alt 111. Harvoni TX 12 weeks.  EOT - 2/18/15, VL UND & normal ast/alt.

4 wks after EOT, VL = UND; normal AST/ALT at 4, 8 and 14 weeks after EOT.  15 weeks after EOT = Undetectable!



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Tess wrote:

Will this affect the availability of Harvoni?


This is just more fighting over $$ that goes on within the Pharma industry.  Litigation costs are already built into the exhorbitant drug prices so it shouldn't have much impact, IMO.  

Abbvie's pricing, along with more HCV txs being FDA approved, will have the greatest impact on cost/availability of Harvoni but I would not expect to see dramatic price reductions right away.  Tx duration will be a significant factor because shorter tx = lower cost. 

This is assuming that Congress doesn't step in with price controls, which is a safe assumption, particularly given the GOP's dominance in Congress. 



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Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.



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Will this affect the availability of Harvoni?



__________________

HCV Gen 1a diagnosed 2001; Labs 11/13/14: VL 1.2 million IU/mL, ast 88, alt 111. Harvoni TX 12 weeks.  EOT - 2/18/15, VL UND & normal ast/alt.

4 wks after EOT, VL = UND; normal AST/ALT at 4, 8 and 14 weeks after EOT.  15 weeks after EOT = Undetectable!



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Hey All

AbbVie has been granted five US patents that specifically claim the use of Sofosbuvir and Ledipasvir, the drug combination that Gilead sales under the name of Harvoni.

Check out the article Seeking alpha - http://www.seekingalpha.com/article/2674915

This will takes years of litigation to sort out and in the end the provisonal patents that were filed long ago will figure in the end result.

matt 



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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 

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