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Hep C Discussion Forum -> Hep C News -> Study on Cognitive Dysfunction and Fatigue
Post Info TOPIC: Study on Cognitive Dysfunction and Fatigue
Tig


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RE: Study on Cognitive Dysfunction and Fatigue
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Hi Wayne,

Thanks for finding that article! Like Rubye, I knew a long time ago that there was something to that idea. Seems it takes an extra decade or two for these researchers and diagnosticians to prove what our symptoms have shown for the same period of time! I think all of these discoveries will help decrease the delays in providing treatment upon diagnosis. Good find buddy!

Tig



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Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Rubye


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While I've known this is true for myself, it is good to hear that it has scientifically been demonstrated that it is indeed so with regard to fatigue and neurotoxicity. I saw a Behaviroal Neurologist about 5 months ago and he attributed my problems to depression rather than Hep C. I don't think he even considered Hep C as the cause of my problems. I declined the antidepressants.

Thanks for sharing this.

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UNDETECTED 5/4/15 - 16 weeks after EOT, 1st treatment - Sovaldi and Olysio, Geno 1a, 67 year old with compensated cirrhosis, over 40 years with HCV.
OldenSlow


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From the American Academy of Neurology:  Recently published data  from a study on imaging abnormalities, neurocognitive function and fatigue in patients with HCV.

"It has long been known that HCV is hepatotoxic; increasingly there is reason to believe that it is neurotoxic as well. While the precise pathophysiologic mechanism remains unclear, findings from the current study as well as others have demonstrated that HCV infection is associated with neurophysiologic and neurobehavioral abnormalities."

"...  Our results suggest that HCV-associated neurologic complications disrupt frontostriatal structures, which may result in increased fatigue and poorer cognitive performance, particularly in those cognitive domains regulated by frontostriatal regions."

Full article:

http://nn.neurology.org/content/2/1/e59.full



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