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Post Info TOPIC: failed treatment with Harvoni... 4 week post treatment labs .. virus detectable


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RE: failed treatment with Harvoni... 4 week post treatment labs .. virus detectable
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Connie, I'm so sorry about the relapse.  You have an amazing attitude!  You really put it in perspective and I thank you for that.  As more and more of us are finishing treatment on Harvoni some of us will probably be in the same boat.  You set the standard for how to deal with it and move on with life.

I am curious about why they don't check for variants before treatment?  Is it maybe too expensive to test everyone? or do they only show up after the treatment?  Just wondering. 

Keep the faith Connie.  New and better treatments are on the way. 

- Tess



__________________

HCV Gen 1a diagnosed 2001; Labs 11/13/14: VL 1.2 million IU/mL, ast 88, alt 111. Harvoni TX 12 weeks.  EOT - 2/18/15, VL UND & normal ast/alt.

4 wks after EOT, VL = UND; normal AST/ALT at 4, 8 and 14 weeks after EOT.  15 weeks after EOT = Undetectable!



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Yes connie relapsed but don't get all down in the dumps...I did 8 weeks of
treatment, virus undetected after 4 weeks, barely detected at 2 weeks... at
4 week post treatment viral load test... viral load 6,000 or so...
whatever... my liver got a 2 month rest.... if I had done 12 weeks it would
have only increased my chances by 2% .. I knew this and this is why I did
not push for 12 weeks....insurance would not approve 12 and I felt like it
was worth the hassle for 2 percent... There are variants you can have that
prevent the treatment from working...they are Q30, Q30H, w30R, y.93H or n,
L32...

OK, the doctors office did a N53Genotype test which checks for all
variants....so the only one that popped up was the 80K, so they did their
job
80 K is only a factor for solvaldi/olysio
... I am the only one from their office that has relapsed... ... gilead was
in the doctor's office yesterday and they are coming out with another new
drug to go with Solvaldi.... i will have to retreat with that... I will be
waiting... feeling better now

OK, so please don't freak out if you are currently treating, I have
always been a strange person which figures I would have a strange
response... hehehe



-- Edited by angelseven on Saturday 21st of February 2015 03:50:11 PM

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62 year old female      1a, f1-2, had virus 40 years   STARTED HARVONI for 8 weeks 11/19/14, relapsed one month after tx  ended in 1/15.  Fibrosis level was only .5 after fibroscan 12/15. Began treatment with Mavyret on January 20, 2018 for 16 weeks!  Ending May 12.

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