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Hep C Discussion Forum -> Post Treatment -> liver function
Post Info TOPIC: liver function
mallani


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RE: liver function
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Hi Robert,

With cirrhotics, there are two things to consider with all medications.

Firstly, many meds are toxic to the liver and smaller doses may be required. Some meds should be avoided altogether.

Secondly, the liver plays a big part in metabolising many meds. When liver function is compromised, meds may not be broken down effectively so the concentrations may rise.

All cirrhotics should discuss any new medication with their doctor.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
robert d


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With cirrhosis how does this affect the way medicines work compared to a healthy liver. Lets say when the doctor prescribes pain meds for surgery on my hand how come the meds: didn't seem to work at the dose prescribe.



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Geno 1a diog 2005 vl 1500000 stage 1&1, 2011 stage 2 to 3 fib stage 3 infl. Started triple x 11/16/2011 VL 15,000,000
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