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Hep C Discussion Forum -> Post Treatment -> Study on genes that cause liver cancer
Post Info TOPIC: Study on genes that cause liver cancer
mallani


Guru

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RE: Study on genes that cause liver cancer
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Duane,

I'll be very interested in your study.

There are already specific genetic disorders that can cause HCC, including haemochromatosis, tyrosinaemia, Wilson's disease, Alpha-1 antitrypsin deficiency and glycogen storage disease.

Also, it is well known that about 80% of HCC's occur in cirrhotic livers (from a variety of causes).

However, patients without any of the above still develop liver cancer and this is often familial. A number of gene or gene mutations have been mentioned. Eventually, we'll all have total gene profiles that predict our likelihood of developing virtually any cancer.

Best of luck mate.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Dzdayscomin


Senior Member

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I was just invited to join a research study thru the Mayo clinic on the study of how our genes determine the susceptibility of getting billary, primary and portal duct liver cancer.

At this point I know very little about it but should have more info after next Fridays blood draw which is all it requires, other than the fact I h ave had cancer.

I will report back more as I learn the specifics of the study.

Duane



__________________

53yr M 1a acq 12/83 cirr pre tx MELD 17  tx nv diag 1/29/12  tx S/O 3/5/14  trans list.

EOT 5/28/14 UND 6/12/14 SVR 8/29/14 MELD 14 dx HCC 9/5/2014 tumor ablation 9/24/14

In the 10K lakes State It's not about us but those around us.
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