Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Hep C Discussion Forum -> Post Treatment -> EOT + 14 SVR - Yeah Babyyyyyyyyyyy
Post Info TOPIC: EOT + 14 SVR - Yeah Babyyyyyyyyyyy
RAGDOLL


Senior Member

Status: Offline
Posts: 123
Date:
RE: EOT + 14 SVR - Yeah Babyyyyyyyyyyy
Permalink  
 

Aloha D,  thanks for sharing your story.  Always good to hear another success, and yes what a journey.  C



__________________

F 63,  1b  1974, no cirrhosis, fibro scan 5.8 F0-F1,fibro test .37 ,V/L 702987, ALT 90, AST 75.  ABBVIE Topaz II on 10-30-14 Viekira Pak no RIBA , EOT 1-22-15 SVR, ALT 37, AST 29, 4-15-15 SVR12 - fibro test .22,  1-21-16 SVR 52 ,  1-21-17 SVR 104! 1-21-18 SVR 3 years ,2020 5 years, 2022 7 years!
JakeAms


Member

Status: Offline
Posts: 32
Date:
Permalink  
 

Another dragon bites the dust!  This is awesome news for you , what an amazing feeling it must be to know you are finally  free.



__________________

JB
Canuck


Guru

Status: Offline
Posts: 3249
Date:
Permalink  
 

doodaman,

What nice home(s) you have!

I am glad this boy is feelin some better!

Thnaks for explaining your logistics, and glad to know your ALT's/AST's etc were followed, and will be followed (I kinda thought they would have been to some degree) it was just the lack of mention of them that just made me curious. 

Sorry, PCR IS my short for the "viral load" test (the HCV RNA quantitative test)

Info:  There are currently three tests used for HCV viral load testing: one is the PCR test - and that was the test I refered to - PCR stands for Polymerase chain reaction - to detect HCV RNA in the blood. This type of quantitative PCR test is very sensitive, and can measure as few as 5-10 IU/mL.

I would have wanted to know my ALT/AST, any other LFT's (liver function tests) they could do along the way, everytime I have a PCR test done (but that's just me). You get a fairly good guess at any major blip in your ALT even if using a dif. lab using a dif. reference range.

I would definitely want to have a EOT+24 week PCR and LFT's done, and I would want these repeated (further along after that) to feel I was well followed (but - that's me!).

You ARE taking very good care of yourself! So good for all of us to know, and for your other friends and your dear parents! Nice. smile C.  



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)
doodaman


Member

Status: Offline
Posts: 10
Date:
Permalink  
 

Hey All,

Thanks for all the kind words. This forum truly does feel like a real 'support' group giving love and encouragement to its members!

To answer your questions Canuck, my doctor that i have been working with for over 12 years is in Hawaii. I remained in the states for my entire 8 week treatment and then flew back to Asia where i live. It was too expensive to fly back to the states just for the Viral Load test so that is why i tested in Thailand which has top medical. I will go back to the states at EOT + 24 for my regular trip back to visit my parents and will have my doctor do the testing through the same lab I have been using for the last decade +. I also chose not to do the basic liver screening tests in Bangkok because I know each lab has its own baselines, especially when it comes to AST and ALT. 

As for Enzyme testing history:

AST - My labs normal range AST is 12 - 42 and I have been testing the high side of normal for the last few years. Right before treatment my numbers where 30 and 4 weeks into treatment the numbers dipped down to 22.

ALT - My labs normal range AST is 3 - 63 and again I have been testing the high side of normal for the last few years. Right before treatment my numbers where 42 and 4 weeks into treatment the numbers dipped down to 16.

I get the feeling those numbers will have dropped even more when i do the test EOT + 24. During my 8 week treatment my energy levels were just so good but then I had a crash EOT where my energy dropped down quite a bit. I get the feeling that after 30 + years with the virus, the short 2 month blast of Harvoni zapped the virus plus whatever else. So at EOT, i just think my body has been resyncing and figuring out what the new definition of Homeostasis is for this poor boy. I am thrilled that EOT + 14 my energy levels are really exploding, what a gift for this 57 year old boy!

Again, one question for all you chiseled veterans here. My Doctor in Hawaii i believe just does the Viral Load test to determine if you are cured. The doctor in Bangkok specifically stated they want to do a PCR test at EOT + 24 to consider one cured. I am not aware of this PCR test, are others here involved with doctors that want the PCR test as well as the Viral Load test to determine whether one is cured?

Alohas,

D



__________________

58 yo - GT 1B - VL 2,300,000 before treatment - A1 - Hepascore F0-F1, Got the Virus in 1985

Harvoni SOT: 03/23/16 UNDET: @ 4 and 8 weeks: EOT: 05/22/16 

 

 
Shadowfax


Guru

Status: Offline
Posts: 681
Date:
Permalink  
 

Congrats on SVR!

It is a nice feeling. I will comment on your question about when we are considered cured. Yes, I agree with Tig that it is said that EOT+12 is considered cured by many HOWEVER, I have a req for EOT+24 that I convinced my Dr. to give to me.

This is the Lab Req from Public Health in Canada that does the VL testing. At the bottom of the form it say's " You are considered cured when two consecutive tests come back after EOT, 3 months apart. When you meet this then no further testing is required unless you are reinfected.

Whether the form is old or not, Personally I think I am cured but also want that EOT + 24 to take one more look at the poor dragons body! smile

Congrats again, it's a great day.

 

SF



__________________

65 yo, GT1A, , Cirrhosis, F-Scan F4 33.5, TX Naive Harvoni 12 wks

SOT 2/9/16 / ALT 187 AST 114 VL 2.3M.    POSTS

EOT 5/2/16  ALT 35/ AST/25  platlets 126 C/B VL UND

EOT +12 7/26/16  ALT 25 /AST 22/ ALP 83  platlets 129 C/B VL UND

EOT + 24 10/18/16 ALT 27/ AST 20/ ALP 71 platlets 153 C UND

 * SVR *
wendyo


Guru

Status: Offline
Posts: 1031
Date:
Permalink  
 

Dan that is quite the journey you have had in every sense of the word. Enjoy your HCV free life! 



__________________

Wendy 53 y/o, DX 1994, geno 1A F1

1999 TX 1 - Inter -non responder 2001 TX 2 - Peg + Riba - viral load tripled and taken off

T3:  Harvoni 12 weeks Sept. 19, 2015 ALT 41 AST 30 VL 541800 UND at EOT and SVR 24 ALT 18 AST 26 platelets 223

 
Sydhanrahan


Guru

Status: Offline
Posts: 552
Date:
Permalink  
 

Doodaman,

that 2 hour crash in your Bangkok hotel room must have been the sweetest nap ever. That whirlwind in your head doesn't just stop there though. I finished treatment in May, got to Post 12 in August and still three weeks later am head spinning. I feel better every day.

i never thought I'd live to see a cure, almost didn't, and now find it hard to believe I have!!! 

Congrats biggrin

Syd



__________________

Contracted Hep C 1969. Genome Type 2, treatment naive. Began 12 week RIBA/sof/Dac on 12/11/15. Cirrhosis. VL before treatment 4m. Treatment extended another 12 weeks without Riba. No virus detected at 9 weeks.
robertsamx


Guru

Status: Offline
Posts: 915
Date:
Permalink  
 

Every time you guys kill a dragon I get better. BIG CONGRATS to you Dan. Thanks for the report-  your cured for sure!!!    RC



__________________

 M-64) 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
Canuck


Guru

Status: Offline
Posts: 3249
Date:
Permalink  
 

Hey doodaman, Big congrats!

I can imagine the degree of difficulty added, the logistics of completing your 8 weeks of Harvoni with feet in both worlds. (Labs in Bankok, home doc elsewhere). Which doc(s) did you and will you end up using for following and for labs/PCR's? You will no doubt have a 24 week PCR and labs planned/coming up.

I think you were und at 4 weeks and at EOT? Did you also have other labs (LFT's) ALT's/AST's done at the same time as well? I imagine you are making sure you are well followed.

I hope you continue to feel better and better now. That was a very well deserved hard crash rejuvenating 2 hour nap you had! Good job you have done! smile C.

 ,



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)
Cheddy


Moderator

Status: Offline
Posts: 795
Date:
Permalink  
 

Splendid news, Dan!  You took action and you nailed it! It's an enormous relief and quite emotional isn't it? There is peace to follow.  Well done, Dan. 



__________________

GT2a, VL 681,500, Less than F1, Treatment Naive

12 wks Sovaldi/Ribavirin, SOT 2/25/16, EOT 5/17/16

UND at 2,4,8 and 12 wks during treatment but ribavirin crazy.

ALT/AST normal EOT

SVR12 8/13/2016!!!!!!!!!  I WON!!

EOT 6 Months 11/12/2016  CURED

 
Tig


Admin

Status: Offline
Posts: 9281
Date:
Permalink  
 

Hi Dan,

Congratulations!!!! You did it my friend and you traveled around the world to do it! I can read the joy and relief if your message. We couldn't be happier for you!

The SVR guidelines have changed over the last couple of years. The Thai doctor may have quoted the old guidelines which stated SVR was determined by an undetected viral load at 6 months post EOT. The new guidelines are 12 weeks post EOT. Some still perform the 24 week viral load test, more out of habit than necessity. 

SVR 12 vs 24



__________________

Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

Hep C FAQ   Lab Ref. Ranges  HCV Resistance

Signature Line Set Up/Abbreviations   Payment Assistance

 
JimmyK


Guru

Status: Offline
Posts: 1839
Date:
Permalink  
 

Greetings,

Another Dragon dead and buried.

 

GREAT NEWS! CONGRATS!

JimmyK



__________________

Harvoni TX 2 12 weeks. UND weeks 4, 12 and now EOT + 4 Weeks. SVR-12 09/29/16. All Glory, Honor and Thanks be to God.

"I go to war with the brothers I trust."
doodaman


Member

Status: Offline
Posts: 10
Date:
Permalink  
 

Hey All,

Jus flew to Bangkok to get my Viral load tested and it came back non-detectable! My understanding is that according to the folks that believe EOT + 12 is the valid time to test, then i do believe I am cured! Its a good day to be alive boys and girls and thanks to TIG and the crew for all of your support during my short treatment.

It was quite emotional when the doctor told me and the first thing i did was call my elderly parents to give the good news. Then i sent Whatsapp messages to about 10 friends around the planet who have or had HEP C to give the good news. Then i went back to my hotel shortly after noon and crashed hard for 2 hours from all the emotion. 

The doctor in Bangkok said something curious i did not hear from my doctors in the states. According to the Thai protocol they don't consider you cured until you take a PCR test at 6 month EOT and come back negative. I never heard of this, what do you all know about such stuff?

Big Hugs To All.

D



__________________

58 yo - GT 1B - VL 2,300,000 before treatment - A1 - Hepascore F0-F1, Got the Virus in 1985

Harvoni SOT: 03/23/16 UNDET: @ 4 and 8 weeks: EOT: 05/22/16 

 

 
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.
Hep C Discussion Forum -> Post Treatment -> EOT + 14 SVR - Yeah Babyyyyyyyyyyy
Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.